In-vitro evaluation of Mg-4.0Zn-0.2Ca alloy for biomedical application

被引：21
作者：
Sun Yu [1 ]
Kong Min-xiu [2 ]
Jiao Xiao-hui [1 ]
机构：
[1] Harbin Med Coll, Stomatol Hosp, Harbin 150001, Peoples R China
[2] Harbin Inst Technol, State Key Lab Robot & Syst, Harbin 150080, Peoples R China
来源：
TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA | 2011年 / 21卷
关键词：
magnesium alloy; biodegradation; biocompatibility; cytotoxicity; MAGNESIUM ALLOYS; SULFATE-SOLUTIONS; PURE MAGNESIUM; VIVO CORROSION; BONE; IMPLANTS; MICROSTRUCTURE; PRECIPITATION; TEMPERATURE; BEHAVIOR;
D O I：
10.1016/S1003-6326(11)61587-2
中图分类号：
TF [冶金工业];
学科分类号：
0806 ;
摘要：
The in-vitro degradation and in-vitro cytotoxicity of the as-extruded Mg-4.0Zn-0.2Ca alloy were investigated. The in-vitro corrosion tests indicate that Zn and Ca elements can dramatically increase the corrosion potential of the as-extruded Mg-4.0Zn-0.2Ca alloy in the simulated body fluid and reduce the degradation rate. The cytotoxicity of the as-extruded Mg-4.0Zn-0.2Ca alloy examined by MTT tests on L929 cells suggest that the alloy has eligible toxicity for implant applications.
引用
收藏
页码：S252 / S257
页数：6
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