Uncoupling protein 2: Adiposity angel and diabetes devil?

被引：14

作者：

O'Rahilly, S ^{[1
]}

机构：

[1] Univ Cambridge, Addenbrookes Hosp, Cambridge CB2 2QQ, England

来源：

NATURE MEDICINE | 2001年 / 7卷 / 07期

关键词：

D O I：

10.1038/89877

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The discovery of a family of proteins with strong homology to the uncoupling protein of brown fat has generated great interest as these molecules might represent therapeutic targets for human obesity. Two recent studies have used genetics to explore the role of one of these proteins, UCP2, in the control of mammalian metabolism and come to rather different conclusions.

引用

页码：770 / 772

页数：3

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