Synthesis of saturated and partially saturated heterocyclic boronic derivatives

The literature on the synthesis of saturated and partially saturated (sp(3)-enriched) boronic acids, boronates, and trifluoroborates is surveyed comprehensively starting from the early 1960s to 2020, focusing mainly on results published in the last decade. The synthetic methods are subdivided into two large groups: those based on the boronate moiety introduction and those commencing from boron-containing substrates. In particular, borylations at various functional groups or even C-H bonds, hydroborations, inter-and intramolecular carboborations, cycloadditions, and metathesis of alkenyl boronates are discussed, together with other methods.(c) 2021 Elsevier Ltd. All rights reserved.