Analysis of the Processes of Extraction-Chromatographic Separation in a Cascade of Mixing-Settling Extractors

被引:4
|
作者
Kostanyan, A. E. [1 ]
Milevsky, N. A. [1 ]
Voshkin, A. A. [1 ]
机构
[1] Russian Acad Sci, Kurnakov Inst Gen & Inorgan Chem, Moscow, Russia
基金
俄罗斯基础研究基金会; 美国国家科学基金会;
关键词
isolation and purification of target components from solutions; liquid extraction; liquid-liquid chromatography; cascade of mixing and settling extractors; CENTRIFUGAL PARTITION CHROMATOGRAPHY; SCALE-UP; COUNTERCURRENT CHROMATOGRAPHY; PROTEIN SEPARATION; NITRATE;
D O I
10.1134/S0040579521050249
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
An analysis of the processes of extraction separation of a mixture of components in a cascade of mixing-settling extractors operating in the elution chromatography mode is carried out for conditions when the mixture of components to be separated is loaded into the cascade in the form of a series of sequential pulse injections separated by short time intervals. Analytical dependencies necessary for modeling periodic and continuous separation processes and examples of modeling such processes are given. It is shown that the use of a serial pulse injection of a solution of a mixture of components makes it possible to increase both the concentration in the separated fractions of the components and the productivity of extraction-chromatographic separation processes by more than an order of magnitude.
引用
收藏
页码:862 / 869
页数:8
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