Synthesis, Characterization, and Biological Activity of Organotin(IV) Complexes with Schiff Bases

被引：4

作者：

Nazneen, S. ^{[1
]}

Ali, S. ^{[2
]}

Shahzadi, S. ^{[2
,3
]}

Shujah, S. ^{[4
]}

机构：

[1] IMCG PG, Dept Chem, F-7-2, Islamabad, Pakistan

[2] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan

[3] Univ Sargodha, Dept Chem, Lyallpur Campus, Faisalabad, Pakistan

[4] Kohat Univ Sci & Technol, Dept Chem, Kohat 26000, Kpk, Pakistan

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2017年 / 87卷 / 12期

关键词：

Schiff base; organotin(IV); IR; NMR; MS; biological activity; CRYSTAL-STRUCTURE; DIORGANOTIN(IV) DERIVATIVES; ACID; CARBOXYLATES;

D O I：

10.1134/S1070363217120404

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesized Schiff base ligands H2L1, N,N'-bis(2-hydroxybenzylidene)1,2-diaminobenzene, and H2L2, N,N'-bis(2-hydroxybenzylidene)hydrazine, reacted with Alk(2)SnCl(2) to give organotin(IV) complexes 1-10. The products were characterized by elemental analysis, FTIR, H-1 and C-13 NMR, and mass spectrometry. All organotin(IV) derivatives with [O,N,O] donor ligands retained their 5-coordinated geometry in solid state and solutions. Most of synthesized complexes exhibited significant antibacterial activity. Cytotoxicity was also tested by using the brine shrimp (Artemia salina) lethality bioassay.

引用

页码：2970 / 2978

页数：9

共 31 条

[1]

Ali M. A., 1977, INORG NUCL CHEM, V29, P265, DOI [10.1016/0022-1902(77)80202-9, DOI 10.1016/0022-1902(77)80202-9]

[2]

[Anonymous], 2013, PURIFICATION INORGAN

[3]

Bhattacharya P. K., 1975, INDIAN CHEM SOC, V52, P104, DOI DOI 10.3109/

[4] ORGANOTIN ESTERS OF 3-(2-FURANYL)-2-PROPENOIC ACID - THEIR CHARACTERIZATION AND BIOLOGICAL-ACTIVITY [J].