Synthesis of hydroxylated pyrrolizidines related to alexine using cycloaddition reactions of functionalized cyclic nitrones

被引：0
|
作者：
Hall, A [1 ]
Meldrum, KP [1 ]
Therond, PR [1 ]
Wightman, RH [1 ]
机构：
[1] HERIOT WATT UNIV,DEPT CHEM,EDINBURGH EH14 4AS,MIDLOTHIAN,SCOTLAND
来源：
SYNLETT | 1997年 / 01期
关键词：
nitrones; cycloaddition; pyrrolizidines; alkaloids;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Cycloaddition reactions of the functionalized Delta(1)-pyrroline-N-oxides 10 and 19 have been used to prepare the hydroxylated pyrrolizidines 6 and 7 respectively, which are related to the natural products alexine and australine.
引用
收藏
页码：123 / &
页数：4
相关论文
共 50 条
  • [41] Divergent synthesis of chiral cyclic azides via asymmetric cycloaddition reactions of vinyl azides
    Nuligonda Thirupathi
    Fang Wei
    Chen-Ho Tung
    Zhenghu Xu
    Nature Communications, 10
  • [42] Synthesis of 5-and 6-membered cyclic hydrazides as organocatalysts for cycloaddition reactions
    Biggs, Robyn A.
    Luo, Xuehong
    Ogilvie, William W.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [43] Synthesis of Natural Products Using Intramolecular Dipolar Cycloaddition Reactions
    Burrell, Adam J. M.
    Coldham, Iain
    CURRENT ORGANIC SYNTHESIS, 2010, 7 (04) : 312 - 331
  • [44] Biocatalytic synthesis of hydroxylated natural products using aldolases and related enzymes
    Fessner, WD
    Helaine, V
    CURRENT OPINION IN BIOTECHNOLOGY, 2001, 12 (06) : 574 - 586
  • [45] Open-chain and cyclic as-functionalized stannylarsines:: Synthesis, reactions, and structure
    Hänssgen, D
    Jeske, R
    Nieger, M
    Roos, W
    ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 2000, 626 (03): : 687 - 691
  • [46] Mannich-type Reactions of Cyclic Nitrones: Effective Methods for the Enantioselective Synthesis of Piperidine-containing Alkaloids
    Lisnyak, Vladislav G.
    Lynch-Colameta, Tessa
    Snyder, Scott A.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (46) : 15162 - 15166
  • [47] N-Benzyl Aspartate Nitrones: Unprecedented Single-Step Synthesis and [3+2] Cycloaddition Reactions with Alkenes
    Nguyen, Thanh Binh
    Martel, Arnaud
    Dhal, Robert
    Dujardin, Gilles
    ORGANIC LETTERS, 2008, 10 (20) : 4493 - 4496
  • [48] Palladium-Catalyzed Coupling Reactions of Thioimidate N-Oxides: Access to α-Alkenyl- and α-Aryl-Functionalized Cyclic Nitrones
    Schleiss, Julie
    Rollin, Patrick
    Tatibouet, Arnaud
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (03) : 577 - 580
  • [49] Novel synthesis of fused-cyclic ethers via cycloaddition reactions of aldehydes and substituted cyclopropanes
    Bonney, Nathaniel
    Horgan, Justin
    Moura-Letts, Gustavo
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [50] Synthesis of Cyclic Azomethine Imines by Cycloaddition Reactions of N-Isocyanates and N-Isothiocyanates
    Bongers, Amanda
    Ranasinghe, Indee
    Lemire, Philippe
    Perozzo, Alyssa
    Vincent-Rocan, Jean-Francois
    Beauchemin, Andre M.
    ORGANIC LETTERS, 2016, 18 (15) : 3778 - 3781
12345