Successful treatment of sarcoidosis-associated pulmonary hypertension with bosentan

被引:29
作者
Foley, Raymond J. [1 ]
Metersky, Mark L. [1 ]
机构
[1] Univ Connecticut, Sch Med, Div Pulm Crit Care Med, Farmington, CT 06030 USA
关键词
sarcoidosis; pulmonary hypertension; endothelin-1; bosentan;
D O I
10.1159/000089815
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Sarcoidosis is a systemic granulomatous disease of unknown etiology, in which the lungs and intrathoracic lymph nodes are predominant sites of involvement. Pulmonary hypertension is a known complication of sarcoidosis. Treatment of sarcoidosis-associated pulmonary hypertension has traditionally focused on the initiation of systemic corticosteroids, but has had inconsistent results. We present a patient with sarcoidosis-associated pulmonary hypertension who achieved substantial clinical improvement with the dual endothelin receptor antagonist bosentan. Copyright (C) 2006 S. Karger AG, Basel.
引用
收藏
页码:211 / 214
页数:4
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