Spectral-temporal analysis of cortical oscillations during lexical processing

被引:20
作者
Tavabi, Kambiz [1 ]
Embick, David [2 ]
Roberts, Timothy P. L. [1 ]
机构
[1] Childrens Hosp Philadelphia, Dept Radiol, Lurie Family Fdn MEG Imaging Ctr, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Linguist, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院;
关键词
alpha band; gamma synchrony; auditory; event-related desynchronization; lexical access; magnetoencephalography; synthetic aperture magnetometry; WORD-RECOGNITION; SPEECH; FREQUENCY; MAGNETOENCEPHALOGRAPHY; KNOWLEDGE; RESPONSES; ALPHA; TASK; MEG;
D O I
10.1097/WNR.0b013e3283476b84
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We investigated the oscillatory neural correlates of auditory lexical processing in healthy adults. Synthetic aperture magnetometry was used to characterize the timing of event-related desynchronization (ERD)/event-related synchronization (ERS) in superior temporal gyri following low-frequency and high-frequency words in contrast to nonwords. ERS and ERD responses were found with both word and nonword stimuli. Analysis of power revealed significantly elevated theta-alpha range (6-14 Hz) ERD in response to words compared with nonwords (left hemisphere: 390-945ms poststimulus). Furthermore, a burst of ERS in the gamma band (40-50 Hz, centered at 410ms poststimulus) distinguished high-frequency and low-frequency words, and also displayed left-hemispheric enhancement following words. Results demonstrate a clear neural correlate of lexical access and provide a basis for further study of spectral-temporal brain activity during language processing. NeuroReport 22:474-478 (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
引用
收藏
页码:474 / 478
页数:5
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