Application of MerCO as a chiral catalyst in asymmetric synthesis: asymmetric borane reduction of ketones

被引：27

作者：

Yang, TK ^{[1
]}

Lee, DS ^{[1
]}

机构：

[1] Natl Chung Hsing Univ, Dept Chem, Taichung 400, Taiwan

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 03期

关键词：

D O I：

10.1016/S0957-4166(98)00504-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The borane reduction of aryl methyl ketones catalyzed by MerCO [( 1R,2S,3R)-3-mercaptocamphan-2-ol] produced I-aryl ethyl alcohols in 92% e.e. at 50 degrees C in toluene. Significant temperature and solvent effects were observed in this reaction. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：405 / 409

页数：5

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