Development of an iridium-based pH sensor for bioanalytical applications

被引:21
作者
Bause, S. [1 ,2 ]
Decker, M. [1 ]
Gerlach, F. [1 ]
Naether, J. [3 ]
Koster, F. [3 ]
Neubauer, P. [2 ]
Vonau, W. [1 ]
机构
[1] Kurt Schwabe Inst Mess & Sensortech eV Meinsberg, Kurt Schwabe Str 4, D-04736 Waldheim, Germany
[2] Tech Univ Berlin, Chair Bioproc Engn, Ackerstrae 76, D-13355 Berlin, Germany
[3] Hsch Mittweida, Univ Appl Sci, Fachgrp Fertigungs & Werkstofftech, Tech Pl 17, Mittweida, Germany
关键词
Iridium oxide; Electrodeposition; pH sensor; Biocompatibility; Bioanalytical application; OXIDE-FILMS; THIN-FILM; ALKALINE-SOLUTIONS; CELL-CULTURE; ELECTRODES; STIMULATION; FABRICATION; DEPOSITION; PALLADIUM; OXIDATION;
D O I
10.1007/s10008-017-3721-1
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
A new iridium-based planar pH sensor for bioanalytical purposes is introduced. The fabrication of the sensor was carried out by a two-stage coating process of different iridium solutions on a platinum thick film surface. The pH response behaviour and the Nernstian characteristics of the double-layer electrode exhibited better results than the single iridium depositions. An almost theoretical Nernstian slope could be obtained as well as a pH response time of about 3 to 5 min in a pH range of 4.01 to 9.18. Furthermore, a biofilm growth of different microorganisms onto the iridium-coated electrodes could be achieved. Afterwards, the viability of the microorganisms was demonstrated via cell plating studies.
引用
收藏
页码:51 / 60
页数:10
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