A facile synthesis, characterization and docking studies of 2-methyl-3-(5-phenyl-4H-(1,2,4)triazol-3-yl)-quinoxaline and its derivatives

被引：0
作者：
Reddy, S. Ramakrishna [1 ]
Reddy, G. Ganga [1 ]
Reddy, Ch Venkata Ramana [1 ]
Reddy, B. Srinivasa [2 ]
Laxminarayana, E. [3 ]
机构：
[1] Jawaharlal Nehru Technol Univ Hyderabad, Dept Chem, Hyderabad 500085, India
[2] Mahatma Gandhi Inst Technol, Hyderabad 500075, India
[3] Sreenidhi Inst Sci & Technol Autonomous Yamnampet, Hyderabad 501301, India
来源：
VIETNAM JOURNAL OF CHEMISTRY | 2022年 / 60卷 / 01期
关键词：
Triazoles; quinoxalines; esterification; condensation; docking studies; BIOLOGICAL EVALUATION; MOLECULAR DOCKING; ONE-POT;
D O I：
10.1002/vjch.202100090
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new series of 2-Methyl-3-(5-phenyl-4H-(1,2,4)triazol-3-yl)-quinoxaline derivatives have been synthesized by simple and efficient method by using 3-methyl-quinoxaline-2-carboxylic acid, 3-methyl-quinoxaline-2-carboxylicacidethylester and 3-methyl-quinoxaline-2-carboxylichydrazide as reaction intermediates in good yields. All the synthesized compounds were characterized by spectral and elemental analysis. The molecular docking studies of 2-Methyl-3-(5-phenyl-4H-(1,2,4)triazol-3-yl)-quinoxalinecarried to predict the anti bacterial potential.
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收藏
页码：92 / 100
页数：9
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