Creation of a severity index for hidradenitis suppurativa that includes a validated quality-of-life measure: the HIDRAscore

被引：18

作者：

Marzano, A., V ^{[1
,2
]}

Chiricozzi, A. ^{[3
]}

Giovanardi, G. ^{[3
]}

Argenziano, G. ^{[4
]}

Bettoli, V ^{[5
]}

Bianchi, L. ^{[6
]}

Dapavo, P. ^{[7
]}

Dini, V ^{[8
]}

Fabbrocini, G. ^{[9
]}

Micali, G. ^{[10
]}

Offidani, A. M. ^{[11
]}

Potenza, C. ^{[12
]}

Prignano, F. ^{[13
]}

Gualberti, G. ^{[14
]}

Saragaglia, V ^{[1
,4
]}

Rongioletti, F. ^{[15
]}

机构：

[1] Fdn IRCCS Ca Granda Osped Maggiore Policlin, UOC Dermatol, Milan, Italy

[2] Univ Milan, Dipartimento Fisiopatol Med Chirurg & Trapianti, Milan, Italy

[3] Catholic Univ, Inst Dermatol, Fdn Policlin Univ A Gemelli IRCCS, Rome, Italy

[4] Univ Campania, Dermatol Unit, Naples, Italy

[5] Univ Ferrara, Dept Clin & Expt Med, Dermatol Unit, Azienda Osped, Ferrara, Italy

[6] Univ Roma Tor Vergata, Dept Dermatol, Policlin Tor Vergata, Rome, Italy

[7] AOU Citta Salute & Sci Torino, Dermatol, Turin, Italy

[8] Univ Pisa, UO Dermatol, Pisa, Italy

[9] Univ Napoli Federico II, Dipartimento Med Clin & Chirurg, UOC Dermatol, Naples, Italy

[10] AOU Policlin, POG Rodol, Dermatol Clin, Catania, Italy

[11] Polytech Marche Univ, Dept Clin & Mol Sci, Dermatol Unit, Ancona, Italy

[12] Sapienza Univ Rome Polo Pontino Latina, Fac Pharm & Med, Dept Medicosurg Sci & Biotechnol, Dermatol Operat Unit Daniele Innocenzi, Rome, Italy

[13] Univ Firenze, Osped Piero Palagi, ASF Dipartimento Chirurg & Med Translaz, Clin Dermatol, Florence, Italy

[14] AbbVie Srl, Rome, Italy

[15] Univ Cagliari, Dept Med Sci & Publ Hlth, Unit Dermatol, Cagliari, Italy

来源：

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | 2020年 / 34卷 / 08期

关键词：

PHYSICIAN COMMUNICATION; SCORING SYSTEM; IMPAIRMENT;

D O I：

10.1111/jdv.16328

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background Hidradenitis suppurativa (HS) is a chronic, debilitating disease with a considerable effect on patient quality of life. Its clinical severity can be measured using different scoring systems; however, few of them include patient-centred parameters. Objective To create a new scoring system for HS that includes a quality-of-life instrument, the HIDRAdisk. Methods This post hoc analysis was carried out within the framework of a multicentre, longitudinal, epidemiologic study conducted over 9 months on quality-of-life aspects of HS. The new severity score was created using as reference a question from the Subject Satisfaction Questionnaire (SSQ) concerning the severity of HS as evaluated by the patient. Associated variables were selected using univariable and multivariable logistic regression models. The discriminant capabilities of the final model and of the final score were evaluated by the area under the receiver operating characteristic curve and the Hosmer-Lemeshow test. Results The study population included 308 patients with HS of any severity grade. According to the results of the regression models, the variables associated with the reference SSQ measure were number of inflammatory nodules, abscesses and draining fistulas; the HIDRAdisk score; and the number of subumbilical lesions. The HIDRAscore is obtained by the sum of the scores associated with the number of these parameters. Possible scores range from 0 to 10. Conclusion The HIDRAscore is a new scoring system for HS severity which, in addition to the clinical evaluation by the physician, includes a validated patient-reported outcome measure, the HIDRAdisk.

引用

页码：1815 / 1821

页数：7