Asymmetric synthesis using palladium catalysts

被引：30

作者：

Sodeoka, M ^{[1
]}

Shibasaki, M

机构：

[1] Sagami Chem Res Ctr, Sagamihara, Kanagawa 229, Japan

[2] Univ Tokyo, Fac Pharmaceut Sci, Bunkyo Ku, Tokyo 113, Japan

来源：

PURE AND APPLIED CHEMISTRY | 1998年 / 70卷 / 02期

关键词：

D O I：

10.1351/pac199870020411

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A catalytic asymmetric aldol reaction proceeding via a chiral palladium(II)) enolate is described. The novel chiral diaquo palladium(II) complexes of (R)-BINAP (9a), and (R)-Tol-BINAP (9b) were prepared in good yield, and their structures were determined by X-ray crystallography. These air- and moisture-stable complexes were found to be excellent catalysts for the asymmetric aldol reaction, and up to 89% ee of asymmetric induction was achieved using these catalysts.

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页码：411 / 414

页数：4

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