DNA thin film coated optical fiber biosensor

被引：20
作者：
Amin, Rashid [1 ,2 ]
Kulkarni, Atul [2 ,3 ]
Kim, Taesung [1 ,3 ]
Park, Sung Ha [1 ,2 ]
机构：
[1] Sungkyunkwan Univ, Sungkyunkwan Adv Inst Nanotechnol SAINT, Suwon 440746, South Korea
[2] Sungkyunkwan Univ, Dept Phys, Suwon 440746, South Korea
[3] Sungkyunkwan Univ, Sch Mech Engn, Suwon 440746, South Korea
来源：
CURRENT APPLIED PHYSICS | 2012年 / 12卷 / 03期
基金：
新加坡国家研究基金会;
关键词：
DNA nanotechnology; Biosensor; Optical fiber sensor; Thin film; Bio-aerosol; SURFACE-PLASMON RESONANCE; NANOTECHNOLOGY; SENSOR; SENSITIVITY; ENTRAPMENT;
D O I：
10.1016/j.cap.2011.11.015
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
We present a simple but highly sensitive biotinylated DNA double crossover thin film coated fiber optic reflectance biosensor (DTF FORS) for the detection of streptavidin aerosols as a building block towards sensing bio-aerosols. The DNA double crossover lattice with biotin was dropped on the polymer optical fiber end face to prepare DNA Thin Film. The streptavidin aerosols were prepared using conventional aerosol technology. The DTF FORS response to streptavidin aerosol was few seconds and the sensor repeatability for air and streptavidin aerosol was found to be excellent. The presented FORS sensing approach, where the film can be changed on the end face of the optical fiber, is expected to detect atmospheric bio-aerosols with great sensitivity and effective specificity. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码：841 / 845
页数：5
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