Lichen planopilaris

被引:79
作者
Kang, Hoon [1 ]
Alzolibani, Abdullateef A. [1 ]
Otberg, Nina [1 ]
Shapiro, Jerry [1 ]
机构
[1] Univ British Columbia, Dept Dermatol & Skin Sci, Vancouver, BC V5Z 1M9, Canada
关键词
alopecia; cicatricial; lichen planopilaris; scarring;
D O I
10.1111/j.1529-8019.2008.00206.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Lichen planopilaris is a chronic scarring alopecia characterized by follicular hyperkeratosis, perifollicular erythema, and loss of follicular orifices. The scalp lesions may be single or multiple and commonly involve the vertex and parietal area. The hair follicles at the margin of the alopecic patches reveal perifollicular erythema. Anagen hairs can be pulled out easily in active lesions. Associated cutaneous, nail, and mucous membrane lichen planus may be present. Commonly encountered symptoms and signs are increased hair shedding, itching, scaling, burning, and tenderness. Differentiation from other cicatricial alopecia can be performed through meticulous evaluation of the clinical, histopathologic, and immunohistopathologic findings. Treatment strategies depend on the disease activity and physician expertise. Although there are no definitive curative modalities, some new discoveries and conceptual advances continue to broaden our treatment options of this complex condition.
引用
收藏
页码:249 / 256
页数:8
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