A Printed Organic Amplification System for Wearable Potentiometric Electrochemical Sensors

被引:63
作者
Shiwaku, Rei [1 ]
Matsui, Hiroyuki [1 ]
Nagamine, Kuniaki [1 ]
Uematsu, Mayu [1 ]
Mano, Taisei [1 ]
Maruyama, Yuki [1 ]
Nomura, Ayako [1 ]
Tsuchiya, Kazuhiko [1 ]
Hayasaka, Kazuma [1 ]
Takeda, Yasunori [1 ]
Fukuda, Takashi [2 ]
Kumaki, Daisuke [1 ]
Tokito, Shizuo [1 ]
机构
[1] Yamagata Univ, Res Ctr Organ Elect ROEL, 4-3-16 Jonan, Yonezawa, Yamagata 9928510, Japan
[2] Tosoh Corp, Funct Polymers Res Lab, 1-8 Kasumi, Yokaichi, Mie 5108540, Japan
基金
日本科学技术振兴机构; 日本学术振兴会;
关键词
FIELD-EFFECT TRANSISTOR; HIGH-PERFORMANCE; ARRAYS;
D O I
10.1038/s41598-018-22265-1
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Electrochemical sensor systems with integrated amplifier circuits play an important role in measuring physiological signals via in situ human perspiration analysis. Signal processing circuitry based on organic thin-film transistors (OTFTs) have significant potential in realizing wearable sensor devices due to their superior mechanical flexibility and biocompatibility. Here, we demonstrate a novel potentiometric electrochemical sensing system comprised of a potassium ion (K+) sensor and amplifier circuits employing OTFT-based pseudo-CMOS inverters, which have a highly controllable switching voltage and closed-loop gain. The ion concentration sensitivity of the fabricated K+ sensor was 34 mV/dec, which was amplified to 160 mV/dec (by a factor of 4.6) with high linearity. The developed system is expected to help further the realization of ultra-thin and flexible wearable sensor devices for healthcare applications.
引用
收藏
页数:8
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