Efficient syntheses of N-alkyl-3-hydroxy-2-methyl-4(1H)-pyridinones from carbohydrate precursors

被引：6
|
作者：
Fox, RC
Taylor, PD
机构：
[1] Univ London Univ Coll, Dept Chem, London WC1H 0AJ, England
[2] Transgenom Inc, San Jose, CA 95131 USA
来源：
SYNTHETIC COMMUNICATIONS | 1999年 / 29卷 / 06期
关键词：
D O I：
10.1080/00397919908086062
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
N-alkyl-3-hydroxy-2-methyl-4(1H)-pyridinohes can be synthesised in reasonable yield from either 1-(3-hydroxy-2-furanyl)ethanone or O-galactosylisomaltol. Since these carbohydrate precursors can be produced from the disaccharide, alpha-D-lactose, a simple and inexpensive transformation into pyridinones is possible.
引用
收藏
页码：989 / 1001
页数：13
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