Persistence of multiple illnesses in World Trade Center rescue and recovery workers: a cohort study

被引:234
作者
Wisnivesky, Juan P. [1 ,2 ]
Teitelbaum, Susan L. [3 ]
Todd, Andrew C. [3 ]
Boffetta, Paolo [4 ]
Crane, Michael [3 ]
Crowley, Laura [3 ]
de la Hoz, Rafael E. [3 ]
Dellenbaugh, Cornelia [3 ]
Harrison, Denise [6 ]
Herbert, Robin [3 ]
Kim, Hyun [7 ]
Jeon, Yunho [3 ]
Kaplan, Julia [3 ]
Katz, Craig [5 ]
Levin, Stephen [3 ]
Luft, Ben [8 ]
Markowitz, Steven [9 ]
Moline, Jacqueline M. [7 ]
Ozbay, Fatih [5 ]
Pietrzak, Robert H. [10 ,11 ]
Shapiro, Moshe [3 ]
Sharma, Vansh [5 ]
Skloot, Gwen [2 ]
Southwick, Steven [10 ,11 ]
Stevenson, Lori A. [3 ]
Udasin, Iris [12 ]
Wallenstein, Sylvan [3 ]
Landrigan, Philip J. [3 ]
机构
[1] Mt Sinai Sch Med, Dept Med, Div Gen Internal Med, New York, NY 10029 USA
[2] Mt Sinai Sch Med, Div Pulm & Crit Care Med, New York, NY 10029 USA
[3] Mt Sinai Sch Med, Dept Prevent Med, New York, NY 10029 USA
[4] Mt Sinai Sch Med, Inst Translat Epidemiol, New York, NY 10029 USA
[5] Mt Sinai Sch Med, Dept Psychiat, New York, NY 10029 USA
[6] NYU, Bellevue Hosp Ctr, Sch Med, Dept Med, New York, NY 10016 USA
[7] Hofstra N Shore LIJ Sch Med, Dept Populat Hlth, Great Neck, NY USA
[8] SUNY Stony Brook, Dept Med, Port Jefferson, NY USA
[9] CUNY Queens Coll, Flushing, NY 11367 USA
[10] Yale Univ, Sch Med, Dept Psychiat, West Haven, CT 06516 USA
[11] Vet Adm Connecticut Healthcare Syst, Natl Ctr Posttraumat Stress Disorder, West Haven, CT USA
[12] Univ Med & Dent New Jersey, Piscataway, NJ 08854 USA
关键词
POSTTRAUMATIC STRESS SYMPTOMS; RESPIRATORY SYMPTOMS; DISASTER RESCUE; LUNG-FUNCTION; HEALTH; FIREFIGHTERS; ASTHMA; WTC; STRATEGIES; EXPOSURE;
D O I
10.1016/S0140-6736(11)61180-X
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background More than 50000 people participated in the rescue and recovery work that followed the Sept 11, 2001 (9/11) attacks on the World Trade Center (WTC). Multiple health problems in these workers were reported in the early years after the disaster. We report incidence and prevalence rates of physical and mental health disorders during the 9 years since the attacks, examine their associations with occupational exposures, and quantify physical and mental health comorbidities. Methods In this longitudinal study of a large cohort of WTC rescue and recovery workers, we gathered data from 27 449 participants in the WTC Screening, Monitoring, and Treatment Program. The study population included police officers, firefighters, construction workers, and municipal workers. We used the Kaplan-Meier procedure to estimate cumulative and annual incidence of physical disorders (asthma, sinusitis, and gastro-oesophageal reflux disease), mental health disorders (depression, post-traumatic stress disorder [PTSD], and panic disorder), and spirometric abnormalities. Incidence rates were assessed also by level of exposure (days worked at the WTC site and exposure to the dust cloud). Findings 9-year cumulative incidence of asthma was 27.6% (number at risk: 7027), sinusitis 42.3% (5870), and gastro-oesophageal reflux disease 39.3% (5650). In police officers, cumulative incidence of depression was 7.0% (number at risk: 3648), PTSD 9.3% (3761), and panic disorder 8.4% (3780). In other rescue and recovery workers, cumulative incidence of depression was 27.5% (number at risk: 4200), PTSD 31.9% (4342), and panic disorder 21.2% (4953). 9-year cumulative incidence for spirometric abnormalities was 41.8% (number at risk: 5769); three-quarters of these abnormalities were low forced vital capacity. Incidence of most disorders was highest in workers with greatest WTC exposure. Extensive comorbidity was reported within and between physical and mental health disorders. Interpretation 9 years after the 9/11 WTC attacks, rescue and recovery workers continue to have a substantial burden of physical and mental health problems. These findings emphasise the need for continued monitoring and treatment of the WTC rescue and recovery population.
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页码:888 / 897
页数:10
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