A dense and strong bonding collagen film for carbon/carbon composites

被引:9
作者
Cao, Sheng [1 ]
Li, Hejun [1 ]
Li, Kezhi [1 ]
Lu, Jinhua [1 ]
Zhang, Leilei [1 ]
机构
[1] Northwestern Polytech Univ, State Key Lab Solidificat Proc, Xian 710072, Shaanxi, Peoples R China
基金
中国国家自然科学基金;
关键词
Osteoblast; Carbon/carbon composites; Collagen; Surface modification; CARBON-CARBON MATERIALS; HYDROTHERMAL TREATMENT; BIOLOGICAL-PROPERTIES; IN-VITRO; COATINGS; HA; BIOCOMPATIBILITY; SCAFFOLDS; POLYMERS;
D O I
10.1016/j.apsusc.2015.04.081
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A strong bonding collagen film was successfully prepared on carbon/carbon (C/C) composites. The surface conditions of the modified C/C composites were detected by contact angle measurements, scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS) and Raman spectra. The roughness, optical morphology, bonding strength and biocompatibility of collagen films at different pH values were detected by confocal laser scanning microscope (CLSM), universal test machine and cytology tests in vitro. After a 4-h modification in 30% H2O2 solution at 100 degrees C, the contact angle on the surface of C/C composites was decreased from 92.3 degrees to 65.3 degrees. Large quantities of hydroxyl, carboxyl and carbonyl functional groups were formed on the surface of the modified C/C composites. Then a dense and continuous collagen film was prepared on the modified C/C substrate. Bonding strength between collagen film and C/C substrate was reached to 8 MPa level when the pH value of this collagen film was 2.5 after the preparing process. With 2-day dehydrathermal treatment (DHT) crosslinking at 105 degrees C, the bonding strength was increased to 12 MPa level. At last, the results of in vitro cytological test showed that this collagen film made a great improvement on the biocompatibility on C/C composites. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:307 / 314
页数:8
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