ODTLES is a novel multi-scale model for 3D turbulent flow based on the one-dimensional-turbulence model of Kerstein ["One-dimensional turbulence: Model formulation and application to homogeneous turbulence, shear flows, and buoyant stratified flows," J. Fluid Mech. 392, 277 (1999)]. Its key distinction is that it is formulated to resolve small-scale phenomena and capture some 3D large-scale features of the flow with affordable simulations. The present work demonstrates this capability by considering four types of wall-bounded turbulent flows. This work shows that spatial profiles of various flow quantities predicted with ODTLES agree fairly well with those from direct numerical simulations. It also shows that ODTLES resolves the near-wall region, while capturing the following 3D flow features: the mechanism increasing tangential velocity fluctuations near a free-slip wall, the large-scale recirculation region in lid-driven cavity flow, and the secondary flow in square duct flow. (C) 2011 American Institute of Physics. [doi:10.1063/1.3664123]