Microbial pathogenesis: Lipid rafts as pathogen portals

被引:134
作者
Rosenberger, CM [1 ]
Brumell, JH
Finlay, BB
机构
[1] Univ British Columbia, Biotechnol Lab, Vancouver, BC V6T 1Z3, Canada
[2] Univ British Columbia, Dept Microbiol & Immunol, Vancouver, BC V6T 1Z3, Canada
[3] Univ British Columbia, Dept Biochem & Mol Biol, Vancouver, BC V6T 1Z3, Canada
基金
加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词
D O I
10.1016/S0960-9822(00)00788-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The route of initial entry influences how host cells respond to intracellular pathogens. Recent studies have demonstrated that a wide variety of pathogens target lipid microdomains in host cell membranes, known as lipid rafts, to enter host cells as an infectious strategy.
引用
收藏
页码:R823 / R825
页数:3
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