A novel 29-nor-3,4-seco-friedelane triterpene and a new guaiane sesquiterpene from the roots of Phyllanthus oxyphyllus

被引：38
作者：
Sutthivaiyakit, S
Nakorn, NN
Kraus, W
Sutthivaiyakit, P
机构：
[1] Ramkhamhang Univ, Fac Sci, Dept Chem, Bangkok 10240, Thailand
[2] Univ Hohenheim, Dept Chem, D-70593 Stuttgart, Germany
[3] Kasetsart Univ, Fac Sci, Dept Chem, Bangkok 10903, Thailand
来源：
TETRAHEDRON | 2003年 / 59卷 / 50期
关键词：
Phyllanthus oxyphyllus; Euphorbiaceae; friedelane; guaiane; cleistanthane; lignans; antioxidant;
D O I：
10.1016/j.tet.2003.10.023
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An unusual 29-nor-3,4-seco-friedelan-4(23),20(30)-dien-3-oic acid and a new 5-hydroxy-6,9-epoxyguaiane have been isolated along with other rare terpenes and lignans from Phyllanthus oxyphyllus roots. Their structures were elucidated from spectroscopic data. The radical scavenging properties of some of these compounds were evaluated. seco-Isolariciresinol showed strong antioxidant activity (IC50 0.017+/-0.001 mM). (C) 2003 Elsevier Ltd. All rights reserved.
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页码：9991 / 9995
页数：5
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