Fully Human Bcma Targeted Chimeric Antigen Receptor T Cells Administered in a Defined Composition Demonstrate Potency at Low Doses in Advanced Stage High Risk Multiple Myeloma

被引:87
作者
Green, Damian J. [1 ,2 ]
Pont, Margot [3 ]
Sather, Blythe Duke [4 ]
Cowan, Andrew J. [3 ,5 ]
Turtle, Cameron J. [1 ,6 ]
Till, Brian G. [1 ,2 ]
Nagengast, Anne M. [3 ]
Libby, Edward N., III [7 ]
Becker, Pamela S. [3 ,8 ]
Coffey, David G. [1 ,2 ]
Tuazon, Sherilyn A. [2 ,9 ]
Wood, Brent [10 ,11 ]
Blake, Michelle [4 ]
Works, Melissa [4 ]
Thompson, Bruce S. [3 ]
Gooley, Ted [2 ]
Appelbaum, Frederick R. [2 ,12 ]
Maloney, David G. [1 ,2 ]
Riddell, Stanley R. [1 ,2 ]
机构
[1] Univ Washington, Dept Med, Seattle, WA USA
[2] Fred Hutchinson Canc Res Ctr, Div Clin Res, 1124 Columbia St, Seattle, WA 98104 USA
[3] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA
[4] Juno Therapeut, Seattle, WA USA
[5] Univ Washington, Div Med Oncol, Seattle, WA 98195 USA
[6] Seattle Canc Care Alliance, Seattle, WA USA
[7] Univ Washington, Med Oncol, Seattle, WA 98195 USA
[8] Univ Washington, Dept Med, Div Hematol, Seattle, WA 98195 USA
[9] Univ Washington, Dept Hematol & Med Oncol, Seattle, WA 98195 USA
[10] Univ Washington, Dept Lab Med, Seattle, WA 98195 USA
[11] Univ Washington, Dept Pathol, Seattle, WA 98195 USA
[12] Univ Washington, Dept Med, Div Med Oncol, Seattle, WA USA
关键词
D O I
10.1182/blood-2018-99-117729
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1011
引用
收藏
页数:3
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