Air pollution and cardiovascular disease

被引:105
作者
Franchini, Massimo [2 ]
Mannucci, Pier Mannuccio [1 ]
机构
[1] IRCCS Ca Granda Maggiore Policlin Hosp Fdn, Sci Direct, I-20122 Milan, Italy
[2] Hosp Mantova, Immunohematol & Transfus Ctr, Mantua, Italy
关键词
ISCHEMIC-HEART-DISEASE; LONG-TERM EXPOSURE; BLOOD-PRESSURE; PARTICULATE MATTER; MYOCARDIAL-INFARCTION; AMBIENT POLLUTION; MORTALITY; RISK; ATHEROSCLEROSIS; ASSOCIATION;
D O I
10.1016/j.thromres.2011.10.030
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
It is well recognized that the exposure to air pollution is associated with many adverse effects on health. A strong epidemiological association has been particularly observed between acute and chronic exposure to air pollutants and the occurrence of cardiovascular diseases. The pathophysiological mechanisms underlying these effects have not been fully identified but potential pathways include endothelial or autonomic dysfunction and systemic reactions such as hypercoagulability, inflammation and oxidative stress. The current knowledge of the short-term and long-term cardiovascular effects of particulate air pollutants is discussed in this review article. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:230 / 234
页数:5
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