Spying on IgE receptor signaling: simply complex, or not

被引：0
|
作者：
Toomre, D [1 ]
机构：
[1] Yale Univ, Sch Med, Dept Cell Biol, New Haven, CT 06520 USA
来源：
JOURNAL OF CELL BIOLOGY | 2005年 / 171卷 / 03期
关键词：
D O I：
10.1083/jcb.200510105
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Plasma membrane organization and the potential role, or not, of lipid raft microdomains in signal transduction is a controversial topic. Cross-correlation fluorescent correlation spectroscopy (CC-FCS) shows promise as a new approach to rapidly probe protein - protein interactions in living cells during signal transduction. CC-FCS data from studies of IgE receptor signaling challenge models of large stable lipid raft signaling domains and reveal a new complexity in the dynamic (re)organization of signaling complexes.
引用
收藏
页码：415 / 417
页数：3
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