The impact of kidney transplantation on 24-hour ambulatory blood pressure in end-stage renal disease patients

被引：8

作者：

Lee, Myung Hyun ^{[1
,2
]}

Ko, Kyung Min ^{[2
]}

Mn, Seung Won ^{[2
]}

Bae, Myoung Nam ^{[1
,2
]}

Choi, Bum Soon ^{[1
,2
]}

Park, Cheol Whee ^{[1
,2
]}

Kim, Yong-Soo ^{[1
,2
]}

Yang, Chul Woo ^{[1
,2
]}

Chung, Byung Ha ^{[1
,2
]}

机构：

[1] Catholic Univ Korea, Coll Med, Seoul St Marys Hosp, Transplant Res Ctr, Seoul, South Korea

[2] Catholic Univ Korea, Coll Med, Seoul St Marys Hosp, Div Nephrol,Dept Internal Med, Seoul, South Korea

来源：

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION | 2015年 / 9卷 / 06期

基金：

新加坡国家研究基金会;

关键词：

Hypertension; circadian rhythm; end stage renal disease; TARGET ORGAN DAMAGE; CIRCADIAN CLOCK; HYPERTENSION; RECIPIENTS; PREVALENCE; MANAGEMENT; CHILDREN;

D O I：

10.1016/j.jash.2015.04.001

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

In this study, we prospectively investigated the impact of kidney transplantation (KT) on the status of hypertension, including circadian rhythm in end-stage renal disease (ESRD) patients. We performed 24-hour ambulatory blood pressure (BP) monitoring and office BP measurement in 48 patients before and 1 year after KT. According to the nocturnal reduction in systolic BP (Delta SBP), the patients were divided into dippers, non-dippers, and reverse dippers. After KT, the mean BP value in office BP and 24-hour ambulatory BP monitoring did not change, but the proportion of patients taking anti-hypertensive drugs and the pill number significantly decreased. In contrast, the mean Delta SBP significantly decreased, and the proportion of non-dippers and reverse dippers did not decrease. Decrease in Delta SBP after KT was associated with inferior allograft function during follow-up. Our study suggests that KT improved the overall BP level, but it did not affect abnormal circadian rhythm in ESRD patients. (C) 2015 American Society of Hypertension. All rights reserved.

引用

页码：427 / 434

页数：8

共 31 条

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