Peptic Ulcer Disease: A Brief Review of Conventional Therapy and Herbal Treatment Options

被引：191

作者：

Kuna, Lucija ^{[1
]}

Jakab, Jelena ^{[2
,3
]}

Smolic, Robert ^{[2
,4
,5
]}

Raguz-Lucic, Nikola ^{[1
]}

Vcev, Aleksandar ^{[2
,5
]}

Smolic, Martina ^{[1
,4
]}

机构：

[1] Josip Juraj Strossmayer Univ Osijek, Fac Dent Med & Hlth Osijek, Dept Pharmacol & Biochem, Osijek 31000, Croatia

[2] Josip Juraj Strossmayer Univ Osijek, Fac Dent Med & Hlth Osijek, Dept Pathophysiol & Physiol Immunol, Osijek 31000, Croatia

[3] Josip Juraj Strossmayer Univ Osijek, Fac Med Osijek, Dept Internal Med, Osijek 31000, Croatia

[4] Josip Juraj Strossmayer Univ Osijek, Fac Med Osijek, Dept Pharmacol, Osijek 31000, Croatia

[5] Univ Hosp Osijek, Dept Internal Med, Osijek 31000, Croatia

来源：

JOURNAL OF CLINICAL MEDICINE | 2019年 / 8卷 / 02期

关键词：

peptic ulcer disease; Helicobacter pylori infection; herbal treatment; HELICOBACTER-PYLORI INFECTION; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; PROTON-PUMP INHIBITOR; INDUCED GASTRITIS; GREEN TEA; ANTIBIOTIC-RESISTANCE; REFLUX ESOPHAGITIS; GARLIC EXTRACT; DUODENAL-ULCER; TRIPLE THERAPY;

D O I：

10.3390/jcm8020179

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Peptic ulcer is a chronic disease affecting up to 10% of the world's population. The formation of peptic ulcers depends on the presence of gastric juice pH and the decrease in mucosal defenses. Non-steroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori (H. pylori) infection are the two major factors disrupting the mucosal resistance to injury. Conventional treatments of peptic ulcers, such as proton pump inhibitors (PPIs) and histamine-2 (H2) receptor antagonists, have demonstrated adverse effects, relapses, and various drug interactions. On the other hand, medicinal plants and their chemical compounds are useful in the prevention and treatment of numerous diseases. Hence, this review presents common medicinal plants that may be used for the treatment or prevention of peptic ulcers.

引用

页数：19

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