Quantum Dots in Cell Biology

被引：120
作者：
Barroso, Margarida M. [1 ]
机构：
[1] Albany Med Coll, Ctr Cardiovasc Sci, Albany, NY 12208 USA
来源：
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY | 2011年 / 59卷 / 03期
关键词：
quantum dots; fluorescence microscopy; single-particle tracking; SPT; fluorescence resonance energy transfer; FRET; receptor; membrane transport; RESONANCE ENERGY-TRANSFER; CONFOCAL FRET MICROSCOPY; LIVING CELLS; LIVE CELLS; SURFACE TRAFFICKING; GOLD NANOPARTICLES; REVERSIBLE DIMERIZATION; TARGETED NANOPARTICLES; PHOSPHOLIPID MICELLES; TRANSFERRIN RECEPTOR;
D O I：
10.1369/0022155411398487
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Quantum dots are semiconductor nanocrystals that have broad excitation spectra, narrow emission spectra, tunable emission peaks, long fluorescence lifetimes, negligible photobleaching, and ability to be conjugated to proteins, making them excellent probes for bioimaging applications. Here the author reviews the advantages and disadvantages of using quantum dots in bioimaging applications, such as single-particle tracking and fluorescence resonance energy transfer, to study receptor-mediated transport. (J Histochem Cytochem 59:237-251, 2011)
引用
收藏
页码：237 / 251
页数：15
相关论文
共 120 条
[1]   Single-particle tracking methods for the study of membrane receptors dynamics [J].
Alcor, Damien ;
Gouzer, Geraldine ;
Triller, Antoine .
EUROPEAN JOURNAL OF NEUROSCIENCE, 2009, 30 (06) :987-997
[2]   Quantum dots as donors in fluorescence resonance energy transfer for the bioanalysis of nucleic acids, proteins, and other biological molecules [J].
Algar, W. Russ ;
Krull, Ulrich J. .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2008, 391 (05) :1609-1618
[3]   Clathrin-Mediated Endocytosis of Quantum Dot-Peptide Conjugates in Living Cells [J].
Anas, Abdulaziz ;
Okuda, Tetsuya ;
Kawashima, Nagako ;
Nakayama, Kenichi ;
Itoh, Tamitake ;
Ishikawa, Mitsuru ;
Biju, Vasudevanpillai .
ACS NANO, 2009, 3 (08) :2419-2429
[4]   Actin restricts FcεRI diffusion and facilitates antigen-induced receptor immobilization [J].
Andrews, Nicholas L. ;
Lidke, Keith A. ;
Pfeiffer, Janet R. ;
Burns, Alan R. ;
Wilson, Bridget S. ;
Oliver, Janet M. ;
Lidke, Diane S. .
NATURE CELL BIOLOGY, 2008, 10 (08) :955-963
[5]   Small, Mobile FcεR1 Receptor Aggregates Are Signaling Competent [J].
Andrews, Nicholas L. ;
Pfeiffer, Janet R. ;
Martinez, A. Marina ;
Haaland, David M. ;
Davis, Ryan W. ;
Kawakami, Toshiaki ;
Oliver, Janet M. ;
Wilson, Bridget S. ;
Lidke, Diane S. .
IMMUNITY, 2009, 31 (03) :469-479
[6]   BASOLATERAL TO APICAL TRANSCYTOSIS IN POLARIZED CELLS IS INDIRECT AND INVOLVES BFA AND TRIMERIC-G PROTEIN SENSITIVE PASSAGE THROUGH THE APICAL ENDOSOME [J].
BARROSO, M ;
SZTUL, ES .
JOURNAL OF CELL BIOLOGY, 1994, 124 (1-2) :83-100
[7]   The interaction between stargazin and PSD-95 regulates AMPA receptor surface trafficking [J].
Bats, Cecile ;
Groc, Laurent ;
Choquet, Daniel .
NEURON, 2007, 53 (05) :719-734
[8]   Nanoconjugation modulates the trafficking and mechanism of antibody induced receptor endocytosis [J].
Bhattacharyya, Sanjib ;
Bhattacharya, Resham ;
Curley, Steven ;
McNiven, Mark A. ;
Mukherjee, Priyabrata .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (33) :14541-14546
[9]   Sensing Caspase 3 Activity with Quantum Dot-Fluorescent Protein Assemblies [J].
Boeneman, Kelly ;
Mei, Bing C. ;
Dennis, Allison M. ;
Bao, Gang ;
Deschamps, Jeffrey R. ;
Mattoussi, Hedi ;
Medintz, Igor L. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (11) :3828-+
[10]   MMP-9 gene silencing by a quantum dot-siRNA nanoplex delivery to maintain the integrity of the blood brain barrier [J].
Bonoiu, Adela ;
Mahajan, Supriya D. ;
Ye, Ling ;
Kumar, Rajiv ;
Ding, Hong ;
Yong, Ken-Tye ;
Roy, Indrajit ;
Aalinkeel, Ravikumar ;
Nair, Bindukumar ;
Reynolds, Jessica L. ;
Sykes, Donald E. ;
Imperiale, Marco A. ;
Bergey, Earl J. ;
Schwartz, Stanley A. ;
Prasad, Paras N. .
BRAIN RESEARCH, 2009, 1282 :142-155
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