Relationship between Heart Disease and Liver Disease: A Two-Way Street

被引：111
作者：
El Hadi, Hamza [1 ,2 ]
Di Vincenzo, Angelo [1 ]
Vettor, Roberto [1 ]
Rossato, Marco [1 ]
机构：
[1] Univ Padua, Dept MedicineDIMED, Internal Med 3, Via Giustiniani 2, I-35100 Padua, Italy
[2] Klinikum Rheine, Dept Med, D-48431 Rheine, Germany
来源：
CELLS | 2020年 / 9卷 / 03期
关键词：
heart failure; arrhythmia; congestive hepatopathy; cardiogenic ischemic hepatitis; cirrhotic cardiomyopathy; liver transplantation; nonalcoholic fatty liver disease; CIRRHOTIC CARDIOMYOPATHY; HYPOXIC HEPATITIS; DIASTOLIC DYSFUNCTION; CARDIAC HEPATOPATHY; OXIDATIVE STRESS; ADIPOSE-TISSUE; NITRIC-OXIDE; TNF-ALPHA; RAT MODEL; IN-VIVO;
D O I：
10.3390/cells9030567
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In clinical practice, combined heart and liver dysfunctions coexist in the setting of the main heart and liver diseases because of complex cardiohepatic interactions. It is becoming increasingly crucial to identify these interactions between heart and liver in order to ensure an effective management of patients with heart or liver disease to provide an improvement in overall prognosis and therapy. In this review, we aim to summarize the cross-talk between heart and liver in the setting of the main pathologic conditions affecting these organs. Accordingly, we present the clinical manifestation, biochemical profiles, and histological findings of cardiogenic ischemic hepatitis and congestive hepatopathy due to acute and chronic heart failure, respectively. In addition, we discuss the main features of cardiac dysfunction in the setting of liver cirrhosis, nonalcoholic fatty liver disease, and those following liver transplantation.
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页数：18
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