The Role of Positron Emission Tomography/Computed Tomography in Planning Radiotherapy in Endometrial Cancer

被引：8

作者：

Simcock, Bryony ^{[1
]}

Narayan, Kailash ^{[1
]}

Drummond, Elizabeth ^{[1
]}

Bernshaw, David ^{[1
]}

Wells, Elizabeth ^{[2
]}

Hicks, Rodney J. ^{[1
]}

机构：

[1] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia

[2] Univ Otago, Biostat & Computat Biol, Populat Hlth, Christchurch, New Zealand

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | 2015年 / 25卷 / 04期

关键词：

PET; CT; Endometrial cancer; Adjuvant radiotherapy; High-risk endometrial cancer; Radiotherapy planning; PET/CT;

D O I：

10.1097/IGC.0000000000000393

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objective The optimal method of assessing disease distribution in endometrial cancer is widely debated. Knowledge of disease distribution assists in planning adjuvant radiotherapy; in this study we used positron emission tomography/computed tomography (PET/CT) to assess disease distribution before radiotherapy. Methods Seventy-three consecutive patients referred to the Peter MacCallum Cancer Centre for adjuvant radiotherapy for endometrial cancer, with either high-risk disease after a hysterectomy or recurrent disease, had a PET/CT before treatment. The findings on PET/CT and clinical course were recorded. Results PET/CT found additional disease in 35% of postoperative patients, changing planned treatment in 31%. In the group with known recurrence, additional disease was found in 72%, changing management in 36%. Conclusions PET/CT is a valuable tool for planning radiotherapy in endometrial cancer.

引用

页码：645 / 649

页数：5

共 11 条

[1] Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma:: multicentre randomised trial [J].

Creutzberg, CL ;

van Putten, WLJ ;

Koper, PCM ;

Lybeert, MLM ;

Jobsen, JJ ;

Wárlám-Rodenhuis, CC ;

De Winter, KAJ ;

Lutgens, LCHW ;

van den Bergh, ACM ;

van de Steen-Banasik, E ;

Beerman, H ;

van Lent, M .

LANCET, 2000, 355 (9213) :1404-1411

[2]

Grigsby PW, 2009, FUTURE ONCOL, V5, P953, DOI [10.2217/fon.09.70, 10.2217/FON.09.70]

[3] Clinical evidence on PET-CT for radiation therapy planning in cervix and endometrial cancers [J].

Haie-Meder, Christine ;

Mazeron, Renaud ;

Magne, Nicolas .

RADIOTHERAPY AND ONCOLOGY, 2010, 96 (03) :351-355

[4] Should positron emission tomography/computed tomography be the first rather than the last test performed in the assessment of cancer? [J].

Hicks, Rodney J. .

CANCER IMAGING, 2012, 12 (02) :315-323

[5] Accuracy of 18-F-FDG PET imaging in the follow up of endometrial cancer patients: Systematic review and meta-analysis of the literature [J].

Kadkhodayan, Sima ;

Shahriari, Sara ;

Treglia, Giorgio ;

Yousefi, Zohreh ;

Sadeghi, Ramin .

GYNECOLOGIC ONCOLOGY, 2013, 128 (02) :397-404

[6] Diagnostic Performance of Fluorine 18 Fluorodeoxyglucose Positron Emission Tomography Imaging for Detection of Primary Lesion and Staging of Endometrial Cancer Patients Systematic Review and Meta-Analysis of the Literature [J].

Kakhki, Vahid Reza Dabbagh ;

Shahriari, Sara ;

Treglia, Giorgio ;

Hasanzadeh, Malihe ;

Zakavi, Seyed Rasoul ;

Yousefi, Zohreh ;

Kadkhodayan, Sima ;

Sadeghi, Ramin .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2013, 23 (09) :1536-1543

[7] Spectrum of FDG PET/CT Findings of Uterine Tumors [J].

Kitajima, Kazuhiro ;

Murakami, Koji ;

Kaji, Yasushi ;

Sugimura, Kazuro .

AMERICAN JOURNAL OF ROENTGENOLOGY, 2010, 195 (03) :737-743

[8] Efficacy of systematic pelvic endometrial cancer (MRC ASTEC trial): a randomised study [J].

Kitchener, H. ;

Swart, A. M. C. ;

Qian, W. ;

Amos, C. ;

Parmar, M. K. B. .

LANCET, 2009, 373 (9658) :125-136

[9]

Mac Manus MP, 2010, Q J NUCL MED MOL IM, V54, P510

[10] Systematic Pelvic Lymphadenectomy vs No Lymphadenectomy in Early-Stage Endometrial Carcinoma: Randomized Clinical Trial [J].

Panici, Pierluigi Benedetti ;

Basile, Stefano ;

Maneschi, Francesco ;

Lissoni, Andrea Alberto ;

Signorelli, Mauro ;

Scambia, Giovanni ;

Angioli, Roberto ;

Tateo, Saverio ;

Mangili, Giorgia ;

Katsaros, Dionyssios ;

Garozzo, Gaetano ;

Campagnutta, Elio ;

Donadello, Nicoletta ;

Greggi, Stefano ;

Melpignano, Mauro ;

Raspagliesi, Francesco ;

Ragni, Nicola ;

Cormio, Gennaro ;

Grassi, Roberto ;

Franchi, Massimo ;

Giannarelli, Diana ;

Fossati, Roldano ;

Torri, Valter ;

Amoroso, Mariangela ;

Croce, Clara ;

Mangioni, Costantino .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2008, 100 (23) :1707-1716

← 1 2 →