Investigation of the antigenic evolution of field isolates using the reverse genetics system of infectious bursal disease virus (IBDV)

被引：30
作者：
Durairaj, Vijay [1 ]
Sellers, Holly S. [1 ]
Linnemann, Erich G. [1 ]
Icard, Alan H. [1 ]
Mundt, Egbert [1 ]
机构：
[1] Univ Georgia, Coll Vet Med, Poultry Diagnost & Res Ctr, Athens, GA 30602 USA
来源：
ARCHIVES OF VIROLOGY | 2011年 / 156卷 / 10期
关键词：
AMINO-ACIDS; NUCLEOTIDE-SEQUENCES; DIFFERENT STRAINS; ESCHERICHIA-COLI; GENOMIC SEGMENT; MOLECULAR-BASIS; SEROTYPES; VP2; GENE; RNA; DIFFERENTIATION;
D O I：
10.1007/s00705-011-1040-x
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The antigenic profiles of over 300 infectious bursal disease virus (IBDV) isolates were analyzed using a panel of monoclonal antibodies in a reverse genetics system. In addition, the sequences of a large portion of the neutralizing-antibody-inducing VP2 of IBDV were determined. Phylogenetic analysis of nucleotide and amino acid sequences in combination with the antigenic profiles obtained using the monoclonal antibody panel, revealed a lack of correlation between antigenicity and isolate's placement within the phylogenetic tree. In-depth analysis of amino acid exchanges revealed that changes within a certain region of the VP2 molecule resulted in differences in the antigenicity of the virus. This comprehensive analysis of VP2 sequences indicated a high selective pressure in the field that was likely due to vaccination programs, which increase the rate of evolution of the virus.
引用
收藏
页码：1717 / 1728
页数：12
相关论文
共 50 条
[31]   DETECTION OF VERY VIRULENT INFECTIOUS BURSAL DISEASE VIRUS FROM A FIELD OUTBREAK IN CENTRAL INDIA [J].
Singh, Azad ;
Bedekar, Megha Kadam ;
Sharma, Rakesh ;
Sarkhel, Bikash Chandra ;
Singh, Sanjeev ;
Jain, Sudhir Kumar .
ACTA VETERINARIA HUNGARICA, 2012, 60 (01) :165-174
[32]   Generation of chicken single chain antibody variable fragments (scFv) that differentiate and neutralize infectious bursal disease virus (IBDV) [J].
Sapats, SI ;
Heine, HG ;
Trinidad, L ;
Gould, GJ ;
Foord, AJ ;
Doolan, SG ;
Prowse, S ;
Ignjatovic, J .
ARCHIVES OF VIROLOGY, 2003, 148 (03) :497-515
[33]   Infectious bursal disease subviral particles displaying the foot-and-mouth disease virus major antigenic site [J].
Remond, Michelle ;
Da Costa, Bruno ;
Riffault, Sabine ;
Parida, Satya ;
Breard, Emmanuel ;
Lebreton, Francoise ;
Zientara, Stephan ;
Delmas, Bernard .
VACCINE, 2009, 27 (01) :93-98
[34]   Characterization of variant infectious bursal disease virus from a broiler farm in Japan using immunized sentinel chickens [J].
Yamazaki, Kenichi ;
Ohta, Hideyuki ;
Kawai, Toru ;
Yamaguchi, Tsuyoshi ;
Obi, Takeshi ;
Takase, Kozo .
JOURNAL OF VETERINARY MEDICAL SCIENCE, 2017, 79 (01) :175-183
[35]   Sequence variability and evolution of the terminal overlapping VP5 gene of the infectious bursal disease virus [J].
Hernandez, Martin ;
Villegas, Pedro ;
Hernandez, Diego ;
Banda, Alejandro ;
Maya, Leticia ;
Romero, Valeria ;
Tomas, Gonzalo ;
Perez, Ruben .
VIRUS GENES, 2010, 41 (01) :59-66
[36]   Genotypic characterization of Indian isolates of infectious bursal disease virus strains by reverse transcription-polymerase chain reaction combined with restriction fragment length polymorphism analysis [J].
Priyadharsini, C. V. ;
Senthilkumar, T. M. A. ;
Raja, P. ;
Kumanan, K. .
ACTA VIROLOGICA, 2016, 60 (01) :34-40
[37]   A Recombinant Baculovirus Expressing VP2 Protein of Infectious Bursal Disease Virus (IBDV) and Chicken Interleukin-18 (ChIL-18) Protein Protects Against Very Virulent IBDV [J].
Kong, Na ;
Wang, Xinhua ;
Zhao, Jianwen ;
Hu, Jingdong ;
Zhang, Hong ;
Zhao, Hongkun .
JOURNAL OF ANIMAL AND VETERINARY ADVANCES, 2011, 10 (20) :2706-2715
[38]   Overexpression of recombinant infectious bursal disease virus (IBDV) capsid protein VP2 in the middle silk gland of transgenic silkworm [J].
Xu, Hanfu ;
Yuan, Lin ;
Wang, Feng ;
Wang, Yuancheng ;
Wang, Riyuan ;
Song, Chunnuan ;
Xia, Qingyou ;
Zhao, Ping .
TRANSGENIC RESEARCH, 2014, 23 (05) :809-816
[39]   Overexpression of recombinant infectious bursal disease virus (IBDV) capsid protein VP2 in the middle silk gland of transgenic silkworm [J].
Hanfu Xu ;
Lin Yuan ;
Feng Wang ;
Yuancheng Wang ;
Riyuan Wang ;
Chunnuan Song ;
Qingyou Xia ;
Ping Zhao .
Transgenic Research, 2014, 23 :809-816
[40]   Molecular characterization of infectious bursal disease virus isolates from nepal based on hypervariable region of VP2 gene [J].
Sharma, K ;
Hair-Bejo, M ;
Omar, AR ;
Aini, I .
ACTA VIROLOGICA, 2005, 49 (01) :59-64
12345