Fast Method for Synthesis of Alkyl and Aryl-N-Methylnitrones

被引：12

作者：

Yavuz, Serkan ^{[1
]}

Ozkan, Hamdi ^{[2
]}

Colak, Naki ^{[3
]}

Yildirir, Yilmaz ^{[1
]}

机构：

[1] Gazi Univ, Fac Sci, Dept Chem, TR-06500 Ankara, Turkey

[2] Cankiri Karatekin Univ, Fac Sci, Dept Chem, TR-18100 Cankiri, Turkey

[3] Hitit Univ, Fac Sci & Arts, Dept Chem, TR-19030 Corum, Turkey

来源：

MOLECULES | 2011年 / 16卷 / 08期

关键词：

nitrone; grinding; solid-phase synthesis; solventless; SOLVENT-FREE SYNTHESIS; CYCLOADDITION REACTIONS; EFFICIENT; OXIDATION; MICROWAVE;

D O I：

10.3390/molecules16086677

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple, fast, efficient and eco-friendly procedure was developed for the synthesis of alkyl and aryl-N-methylnitrones. The corresponding nitrones of aromatic aldehydes, aliphatic aldehydes and alicyclic carbonyl compounds were prepared from N-methylhydroxylamine hydrochloride and Na2CO3-Na2SO4 by simply grinding at room temperature without using solvent.

引用

页码：6677 / 6683

页数：7

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