2-amino-2-oxazolines, part 9:: Synthesis and pharmacological evaluation of N-phenyl-N′-[1-[3-(1-aryl-4-piperazinyl)propan-2-ol]]ureas

被引：0
|
作者：
Bosc, JJ [1 ]
Jarry, C [1 ]
机构：
[1] Univ Bordeaux 2, UFR Sci Pharmaceut, Chim Phys Lab, F-33076 Bordeaux, France
来源：
ARCHIV DER PHARMAZIE | 1998年 / 331卷 / 09期
关键词：
2-amino-2-oxazoline; 3-phenylcarbamoyl-2-iminooxazolidine; N-phenyl-N '-[l-[3-(1-aryl-4-piperazinyl)-propan-2-ol]]urea; antiallergic and analgesic activities;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
N-Phenyl-N'-[1-[3-(1-aryl-4-piperazinyl)propan-2-ol]]ureas (3) were synthesized from the 3-phenylcarbamoyl-5-[( 1-aryl-4-piperazinyl)methyl]-2-iminooxazolidines (1) via the corresponding 2-oxazolidinones (2). The prepared compounds were screened for their antiallergic and analgesic activities.
引用
收藏
页码：291 / 293
页数：3
相关论文
共 50 条
  • [31] Synthesis of potentially β-blocking practolol derivatives:: (E+Z)-3-[4-(3-iodoprop-2-enyloxyc arbonylamino)phenoxy]-1-(isopropylamino)propan-2-ol
    Apparu, M
    Ben Tiba, Y
    Léo, PM
    Fagret, D
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2000, 2000 (06) : 1007 - 1012
  • [32] 1-{2-( 4-Chlorobenzyloxy)-2-[4-(morpholin- 4- yl) phenyl] ethyl}-1H-benzimidazole propan-2-ol monosolvate
    Guven, Ozden Ozel
    Capanlar, Seval
    Adler, Philip D. F.
    Coles, Simon J.
    Hokelek, Tuncer
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O1437 - +
  • [33] Synthesis, characterization, and pharmacological evaluation of 1-[2-(6-nitro-4-oxo-2-phenyl-4H-quinazolin-3-yl)-ethyl]-3-phenyl ureas
    Aniruddhasinh M. Rana
    Kishor R. Desai
    Smita Jauhari
    Medicinal Chemistry Research, 2013, 22 : 225 - 233
  • [34] Synthesis, characterization, and pharmacological evaluation of 1-[2-(6-nitro-4-oxo-2-phenyl-4H-quinazolin-3-yl)-ethyl]-3-phenyl ureas
    Rana, Aniruddhasinh M.
    Desai, Kishor R.
    Jauhari, Smita
    MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (01) : 225 - 233
  • [35] N,N,N′,N′-Tetrakis{3-[1-(2-hydroxy-4-methoxy-phenyl)ethenylamino] propyl}ethylenediamine
    Xu, Xing-You
    Xu, Tong-Tao
    Wang, Da-Qi
    Gao, Jian
    Li, Dao-Nian
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O103 - O104
  • [36] Synthesis of 2-(6-substituted quinolin-4-yl)-1-(4-aryl-1H-1,2,3-triazol-1-yl) propan-2-ol as potential antifungal and antitubercular agents
    Shinde, Abhijit
    Thakare, Prashant P.
    Nandurkar, Yogesh
    Bhoye, Manish
    Chavan, Abhijit
    Mhaske, Pravin C.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY REPORTS, 2023, 7
  • [37] Regioselective alkylation of phenol with cyclopentanol over montmorillonite K10:: An efficient synthesis of 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]propan-2-ol {(S)-penbutolol}
    Phukan, P
    Sudalai, A
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1999, (20): : 3015 - 3018
  • [38] The synthesis and structure of 1-[3-{(2-hydroxybenzylidene)amino}phenyl]ethanone
    De, Rajib Lal
    Mukherjee, Jaydeep
    Mandal, Mahuya
    Roy, Lovely
    Bhowal, Ruchika
    Banerjee, Indrajit
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2009, 48 (04): : 595 - 598
  • [39] 1-(4-Hydroxyphenyl)-3-(2,4,6-trimethoxy-phenyl)propan-1-one
    Lu, YB
    Zheng, QT
    Lu, Y
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2006, 62 : O469 - O470
  • [40] SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF 1-(2,4-DISUBSTITUTED PHENOXY)-3-[N1-(N4-ARYLPIPERAZINYL)]PROPANES AND 1-(4-CHLOROBENZOYL)-3-SUBSTITUTED-6-METHOXY-2-(4-[3-N1-(N4-PHENYLPIPERAZINYL)PROPOXY]PHENYL)INDOLES
    AGARWAL, SK
    SAXENA, AK
    JAIN, PC
    ANAND, N
    SRIMAL, RC
    DHAWAN, BN
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1991, 30 (04): : 413 - 416
12345