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Just passing through: The auxin gradient of the root meristem
被引:6
|作者:
Guillotin, Bruno
[1
]
Birnbaum, Kenneth D.
[1
]
机构:
[1] NYU, Dept Biol, Ctr Genom & Syst Biol, New York, NY 10003 USA
来源:
GRADIENTS AND TISSUE PATTERNING
|
2020年
/
137卷
关键词:
BOX PROTEIN TIR1;
STEM-CELL NICHE;
TRANSCRIPTION FACTOR;
MICRORNA MIR396;
SMALL-MOLECULE;
ARABIDOPSIS;
BIOSYNTHESIS;
GROWTH;
TRANSPORT;
GENES;
D O I:
10.1016/bs.ctdb.2019.12.001
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
The root meristem-one of the plant's centers of continuous growth-is a conveyer belt in which cells of different identities are pushed through gradients along the root's longitudinal axis. An auxin gradient has long been implicated in controlling the progression of cell states in the root meristem. Recent work has shown that a PLETHORA (PLT) protein transcription factor gradient, which is under a delayed auxin response, has a dose-dependent effect on the differentiation state of cells. The direct effect of auxin concentration on differential transcriptional outputs remains unclear. Genomic and other analyses of regulatory sequences show that auxin responses are likely controlled by combinatorial inputs from transcription factors outside the core auxin signaling pathway. The passage through the meristem exposes cells to varying positional signals that could help them interpret auxin inputs independent of gradient effects. One open question is whether cells process information from the changes in the gradient over time as they move through the auxin gradient.
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页码:433 / 454
页数:22
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