The analysis of substituted cathinones. Part 1: Chemical analysis of 2-, 3-and 4-methylmethcathinone

被引:69
作者
Power, John D. [1 ]
McGlynn, Peggy [1 ]
Clarke, Karen [1 ]
McDermott, Sean D. [1 ]
Kavanagh, Pierce [2 ]
O'Brien, John [3 ]
机构
[1] Garda HQ, Forens Sci Lab, Dublin 8, Ireland
[2] St James Hosp, Trinity Ctr Hlth Sci, Sch Med, Dept Pharmacol & Therapeut, Dublin 8, Ireland
[3] Trinity Coll Dublin, Sch Chem, Dublin 2, Ireland
关键词
Forensic; Mephedrone; Chemical; Analysis; Synthesis; Drug; MEPHEDRONE; SUBSTANCE; KETONES;
D O I
10.1016/j.forsciint.2011.04.020
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
The ring substituted methyl isomers of methcathinone, 2-, 3- and 4-methylmethcathinone were analysed. The 2- and 3- isomers were synthesized. The 4-methylmethcathinone isomer is also known as mephedrone and has been widely studied. We present GCMS, NMR and IR data for the three isomers. We show that the three isomers can be separated by GCMS and that the IR spectra for the three compounds can be used to distinguish between them. A seized sample was analysed and it was found to contain 4-methylmethcathinone and benzocaine. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:6 / 12
页数:7
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