Alcohol consumption and risk of renal cell cancer: the NIH-AARP diet and health study

被引：31

作者：

Lew, J. Q. ^{[1
,2
]}

Chow, W-H ^{[1
]}

Hollenbeck, A. R. ^{[3
]}

Schatzkin, A. ^{[1
]}

Park, Y. ^{[1
]}

机构：

[1] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA

[2] Washington Univ, St Louis Childrens Hosp, Med Ctr, St Louis, MO 63110 USA

[3] AARP, Washington, DC USA

来源：

BRITISH JOURNAL OF CANCER | 2011年 / 104卷 / 03期

关键词：

alcohol; renal cell cancer; cohort; KIDNEY CANCER; CARCINOMA; WOMEN; DRINKING; COHORT; BEVERAGES; GENDER;

D O I：

10.1038/sj.bjc.6606089

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

BACKGROUND: The effect of moderate to heavy drinking (>15 g per day) on renal cell cancer (RCC) risk is unclear. METHOD The relationship between alcohol consumption and RCC was examined in the NIH-AARP Diet and Health Study (n = 49 2187, 1814 cases). RESULTS: Compared with >0 to <5 g per day of alcohol consumption, the multivariate relative risk (95% confidence intervals) for 15 to <3C and >= 30g per day was, 0.75 (0.63-0.90) and 0.71 (0.59-0.85), respectively, in men and 0.67 (0.42-1.07) and 0.43 (0.22-0.84), respectively, in women. CONCLUSION: Alcohol consumption was inversely associated with RCC in a dose-response manner. The inverse association may be extended to >= 30 g per day of alcohol intake. British Journal of Cancer (2011) 104, 537-541. doi:10.1038/sj.bjc.6606089 www.bjcancer.com Published online 18 January 2011 (C) 2011 Cancer Research UK

引用

页码：537 / 541

页数：5

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