Biflavonoids from Fumana procumbens (Dunal) Gren. & Godr

The first phytochemical investigation on the aerial parts of Fumana procumbens (Dunal) Gren. & Godr. led to the isolation and identification of six compounds, including two biflavonoids, i.e. dihydrodaphnodorin B (1) and daphnodorin B (2); three flavonoids, i.e. quercitrin (3), myricitrin (4), and quercetin (5); and a flavan derivative, i.e. epigallocatechin (6). The structures of the compounds were elucidated by extensive 1D- and 2D-NMR spectroscopic analysis in combination with MS experiments. This is the first report on the isolation of biflavonoids from the genus Fumana and from the family Cistaceae. (C) 2017 Elsevier Ltd. All rights reserved.