A case of chronic myelogenous leukemia with the T315I mutation who progressed to myeloid blast phase and was successfully treated with asciminib

被引：3
作者：
Tomassetti, Sarah [1 ,2 ,3 ]
Lee, Jennifer [1 ,2 ,3 ]
Qing, Xin [2 ,3 ,4 ]
机构：
[1] Univ Calif Los Angeles, Div Hematol & Oncol, Harbor UCLA Med Ctr, Los Angeles, CA USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA
[3] Lundquist Res Inst, 1000 West Carson St N18, Torrance, CA 90502 USA
[4] Univ Calif Los Angeles, Dept Pathol, Harbor UCLA Med Ctr, Los Angeles, CA 90024 USA
来源：
CLINICAL CASE REPORTS | 2022年 / 10卷 / 11期
关键词：
asciminib; blast phase; chronic myelogenous leukemia; T315I mutation; MARROW-TRANSPLANTATION; FOLLOW-UP; IMATINIB; INHIBITOR; DASATINIB; HYDROXYUREA; INTERFERON; EFFICACY; BUSULFAN; 5-YEAR;
D O I：
10.1002/ccr3.6478
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Patients with chronic myelogenous leukemia (CML) harboring the T315I mutation who progress to blast phase CML while on ponatinib may be successfully treated with asciminib monotherapy following induction therapy with cytotoxic chemotherapy.
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页数：6
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