A case of chronic myelogenous leukemia with the T315I mutation who progressed to myeloid blast phase and was successfully treated with asciminib

被引：4
作者：
Tomassetti, Sarah [1 ,2 ,3 ]
Lee, Jennifer [1 ,2 ,3 ]
Qing, Xin [2 ,3 ,4 ]
机构：
[1] Univ Calif Los Angeles, Div Hematol & Oncol, Harbor UCLA Med Ctr, Los Angeles, CA USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA
[3] Lundquist Res Inst, 1000 West Carson St N18, Torrance, CA 90502 USA
[4] Univ Calif Los Angeles, Dept Pathol, Harbor UCLA Med Ctr, Los Angeles, CA 90024 USA
来源：
CLINICAL CASE REPORTS | 2022年 / 10卷 / 11期
关键词：
asciminib; blast phase; chronic myelogenous leukemia; T315I mutation; MARROW-TRANSPLANTATION; FOLLOW-UP; IMATINIB; INHIBITOR; DASATINIB; HYDROXYUREA; INTERFERON; EFFICACY; BUSULFAN; 5-YEAR;
D O I：
10.1002/ccr3.6478
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Patients with chronic myelogenous leukemia (CML) harboring the T315I mutation who progress to blast phase CML while on ponatinib may be successfully treated with asciminib monotherapy following induction therapy with cytotoxic chemotherapy.
引用
收藏
页数：6
相关论文
共 26 条
[1]   The role of stem cell transplantation for chronic myelogenous leukemia in the 21st century [J].
Barrett, A. John ;
Ito, Sawa .
BLOOD, 2015, 125 (21) :3230-3235
[2]   Life Expectancy of Patients With Chronic Myeloid Leukemia Approaches the Life Expectancy of the General Population [J].
Bower, Hannah ;
Bjorkholm, Magnus ;
Dickman, Paul W. ;
Hoglund, Martin ;
Lambert, Paul C. ;
Andersson, Therese M. -L. .
JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (24) :2851-+
[3]   Integrative genomic analysis reveals cancer-associated mutations at diagnosis of CML in patients with high-risk disease [J].
Branford, Susan ;
Wang, Paul ;
Yeung, David T. ;
Thomson, Daniel ;
Purins, Adrian ;
Wadham, Carol ;
Shahrin, Nur Hezrin ;
Marum, Justine E. ;
Nataren, Nathalie ;
Parker, Wendy T. ;
Geoghegan, Joel ;
Feng, Jinghua ;
Shanmuganathan, Naranie ;
Mueller, Martin C. ;
Dietz, Christian ;
Stangl, Doris ;
Donaldson, Zoe ;
Altamura, Haley ;
Georgievski, Jasmina ;
Braley, Jodi ;
Brown, Anna ;
Hahn, Christopher ;
Walker, Ieuan ;
Kim, Soo-Hyun ;
Choi, Soo-Young ;
Park, Sa-Hee ;
Kim, Dong-Wook ;
White, Deborah L. ;
Yong, Agnes S. M. ;
Ross, David M. ;
Scott, Hamish S. ;
Schreiber, Andreas W. ;
Hughes, Timothy P. .
BLOOD, 2018, 132 (09) :948-961
[4]  
Bucelli C, 2017, CASE REP HEMATOL, V2017, DOI 10.1155/2017/6167345
[5]   Third-line therapy for chronic myeloid leukemia: current status and future directions [J].
Cortes, Jorge ;
Lang, Fabian .
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 14 (01)
[6]   Bosutinib Versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia: Results From the Randomized BFORE Trial [J].
Cortes, Jorge E. ;
Gambacorti-Passerini, Carlo ;
Deininger, Michael W. ;
Mauro, Michael J. ;
Chuah, Charles ;
Kim, Dong-Wook ;
Dyagil, Irina ;
Glushko, Nataliia ;
Milojkovic, Dragana ;
le Coutre, Philipp ;
Garcia-Gutierrez, Valentin ;
Reilly, Laurence ;
Jeynes-Ellis, Allison ;
Leip, Eric ;
Bardy-Bouxin, Nathalie ;
Hochhaus, Andreas ;
Brummendorf, Tim H. .
JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (03) :231-+
[7]   Final 5-Year Study Results of DASISION: The Dasatinib Versus Imatinib Study in Treatment-Naive Chronic Myeloid Leukemia Patients Trial [J].
Cortes, Jorge E. ;
Saglio, Giuseppe ;
Kantarjian, Hagop M. ;
Baccarani, Michele ;
Mayer, Jiri ;
Boque, Concepcion ;
Shah, Neil P. ;
Chuah, Charles ;
Casanova, Luis ;
Bradley-Garelik, Brigid ;
Manos, George ;
Hochhaus, Andreas .
JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (20) :2333-U54
[8]   Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia [J].
Druker, Brian J. ;
Guilhot, Francois ;
O'Brien, Stephen G. ;
Gathmann, Insa ;
Kantarjian, Hagop ;
Gattermann, Norbert ;
Deininger, Michael W. N. ;
Silver, Richard T. ;
Goldman, John M. ;
Stone, Richard M. ;
Cervantes, Francisco ;
Hochhaus, Andreas ;
Powell, Bayard L. ;
Gabrilove, Janice L. ;
Rousselot, Philippe ;
Reiffers, Josy ;
Cornelissen, Jan J. ;
Hughes, Timothy ;
Agis, Hermine ;
Fischer, Thomas ;
Verhoef, Gregor ;
Shepherd, John ;
Saglio, Giuseppe ;
Gratwohl, Alois ;
Nielsen, Johan L. ;
Radich, Jerald P. ;
Simonsson, Bengt ;
Taylor, Kerry ;
Baccarani, Michele ;
So, Charlene ;
Letvak, Laurie ;
Larson, Richard A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (23) :2408-2417
[9]   DISAPPEARANCE OF PH1-POSITIVE CELLS IN 4 PATIENTS WITH CHRONIC GRANULOCYTIC LEUKEMIA AFTER CHEMOTHERAPY, IRRADIATION AND MARROW TRANSPLANTATION FROM AN IDENTICAL TWIN [J].
FEFER, A ;
CHEEVER, MA ;
THOMAS, ED ;
BOYD, C ;
RAMBERG, R ;
GLUCKSBERG, H ;
BUCKNER, CD ;
STORB, R .
NEW ENGLAND JOURNAL OF MEDICINE, 1979, 300 (07) :333-337
[10]   Safety and efficacy of asciminib treatment in chronic myeloid leukemia patients in real-life clinical practice [J].
Garcia-Gutierrez, Valentin ;
Luna, Alejandro ;
Alonso-Dominguez, Juan M. ;
Estrada, Natalia ;
Boque, Concepcion ;
Xicoy, Blanca ;
Giraldo, Pilar ;
Angona, Anna ;
Alvarez-Larran, Alberto ;
Sanchez-Guijo, Fermin ;
Ramirez, Maria Jose ;
Mora, Elvira ;
Velez, Patricia ;
Rosell, Ana ;
Colorado Araujo, Mercedes ;
Cuevas, Beatriz ;
Sagues, Miguel ;
Cortes, Montserrat ;
Encinas, Manuel Perez ;
Casado Montero, Luis Felipe ;
Moreno Vega, Melania ;
Serrano, Luis ;
Gomez, Valle ;
Garcia-Hernandez, Carmen ;
Lakhwani, Sunil ;
Paz Coll, Antonio ;
de Paz, Raquel ;
Suarez-Varela, Sara ;
Fernandez-Ruiz, Andres ;
Perez Lopez, Raul ;
Ortiz-Fernandez, Almudena ;
Jimenez-Velasco, Antonio ;
Steegmann-Olmedillas, Juan Luis ;
Hernandez-Boluda, Juan Carlos .
BLOOD CANCER JOURNAL, 2021, 11 (02)
123