BACE1 in central nervous system myelination revisited

被引:14
|
作者
Treiber, H. [1 ]
Hagemeyer, N. [1 ]
Ehrenreich, H. [1 ]
Simons, M. [2 ]
机构
[1] Max Planck Inst Expt Med, Div Clin Neurosci, D-3400 Gottingen, Germany
[2] Univ Gottingen, Dept Neurol, D-3400 Gottingen, Germany
关键词
BETA-SECRETASE; DISEASE; MICE;
D O I
10.1038/mp.2011.140
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:237 / 239
页数:4
相关论文
共 50 条
  • [21] Cloning and expression of the rat BACE1 promoter
    Lange-Dohna, C
    Zeitschel, U
    Gaunitz, F
    Perez-Polo, JR
    Bigl, V
    Rossner, S
    JOURNAL OF NEUROSCIENCE RESEARCH, 2003, 73 (01) : 73 - 80
  • [22] Characterization of Cerebrospinal Fluid BACE1 Species
    Lopez-Font, Inmaculada
    Boix, Claudia P.
    Zetterberg, Henrik
    Blennow, Kaj
    Saez-Valero, Javier
    MOLECULAR NEUROBIOLOGY, 2019, 56 (12) : 8603 - 8616
  • [23] Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half-life
    Liu, Lei
    Lauro, Bianca M.
    Ding, Li
    Rovere, Matteo
    Wolfe, Michael S.
    Selkoe, Dennis J.
    ALZHEIMERS & DEMENTIA, 2019, 15 (09) : 1183 - 1194
  • [24] BACE1 and BACE2 enzymatic activities in Alzheimer's disease
    Ahmed, Rachel R.
    Holler, Christopher J.
    Webb, Robin L.
    Li, Feng
    Beckett, Tina L.
    Murphy, M. Paul
    JOURNAL OF NEUROCHEMISTRY, 2010, 112 (04) : 1045 - 1053
  • [25] Synthesis, radiolabeling, and evaluation of a potent β-site APP cleaving enzyme (BACE1) inhibitor for PET imaging of BACE1 in vivo
    Pan, Lili
    He, Qian
    Wu, Yi
    Zhang, Ni
    Cai, Huawei
    Yang, Bo
    Wang, Yuxi
    Li, Yunchun
    Wu, Xiaoai
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 59
  • [26] Seizure-6 proteins highlight BACE1 functions in neurobiology
    Pigoni, Martina
    Gunnersen, Jenny M.
    Lichtenthaler, Stefan F.
    ONCOTARGET, 2017, 8 (05) : 7214 - 7215
  • [27] miR-29c regulates BACE1 protein expression
    Zong, Yuanyuan
    Wang, Hailin
    Dong, Wei
    Quan, XiongZhi
    Zhu, Hua
    Xu, YanFeng
    Huang, Lan
    Ma, Chunmei
    Qin, Chuan
    BRAIN RESEARCH, 2011, 1395 : 108 - 115
  • [28] Expression of Bace1 is positive with the progress of atherosclerosis and formation of foam cell
    Chen, Linmu
    Huang, Yunxiu
    Guo, Jun
    Li, Yunjing
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 528 (03) : 440 - 446
  • [29] Consecutive Analysis of BACE1 Function on Developing and Developed Neuronal Cells
    Kamikubo, Yuji
    Takasugi, Nobumasa
    Niisato, Kazue
    Hashimoto, Yoshie
    Sakurai, Takashi
    JOURNAL OF ALZHEIMERS DISEASE, 2017, 56 (02) : 641 - 653
  • [30] Implications for BACE1 Inhibitor Clinical Trials: Adult Conditional BACE1 Knockout Mice Exhibit Axonal Organization Defects in the Hippocampus
    Vassar, R.
    JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE, 2019, 6 (02): : 78 - 84