Title: Runx1 Is Indispensable for Leukemia Development Induced By Cbfb-MYH11

被引：0
|
作者：
Zhen, Tao [1 ,2 ]
Kwon, Erika Mijin [2 ]
Hyde, R. Katherine [3 ,4 ]
Zhao, Ling [5 ]
Lopez, Guadalupe [1 ]
Alemu, Lemlem [6 ]
Liu, Paul P. [2 ]
机构：
[1] NHGRI, Translat & Funct Genom Branch, NIH, Bethesda, MD 20892 USA
[2] NHGRI, Oncogenesis & Dev Sect, NIH, Bethesda, MD 20892 USA
[3] Univ Nebraska Med Ctr, Dept Biochem & Mol Biol, Omaha, NE USA
[4] Univ Nebraska Med Ctr, Fred & Pamela Buffet Canc Ctr, Omaha, NE USA
[5] NHGRI, Oncogenesis & Dev Sect, Bethesda, MD 20892 USA
[6] NHLBI, Hematol Branch, NIH, Bethesda, MD 20892 USA
来源：
BLOOD | 2018年 / 132卷
关键词：
D O I：
10.1182/blood-2018-99-116930
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1337
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11
    Kundu, M
    Chen, A
    Anderson, S
    Kirby, M
    Xu, LP
    Castilla, LH
    Bodine, D
    Liu, PP
    BLOOD, 2002, 100 (07) : 2449 - 2456
  • [42] A CASE OF ACUTE MYELOID LEUKEMIA WITH CO-EXISTING CBFB-MYH11 AND BCR-ABL1 FUSION GENES
    Imanaka, Yusuke
    Matsumura, Risa
    Mizoguchi, Yoko
    Eto, Shohei
    Shimomura, Maiko
    Karakawa, Shuhei
    Doi, Takehiko
    Kawaguchi, Hiroshi
    Tomizawa, Daisuke
    Okada, Satoshi
    PEDIATRIC BLOOD & CANCER, 2022, 69
  • [43] Clinical Impact of Minimal Residual Disease (MRD) Monitoring in AML with PM-Rara, CBFB-MYH11, and RUNX1-RUNX1T1: A Study on 600 Patients
    Haferlach, Torsten
    Meggendorfer, Manja
    Schnittger, Susanne
    Fasan, Annette
    Kern, Wolfgang
    Haferlach, Claudia
    BLOOD, 2015, 126 (23)
  • [44] The C-Terminal of MYH11 Is Required for Cbfb-MYH11 Activity During Embryonic Hematopoiesis and Leukemogenesis
    Hyde, R. Katherine
    Kamikubo, Yasuhiko
    Zhao, Ling
    Alemu, Lemlem
    Garrett, Lisa
    Liu, Pu Paul
    BLOOD, 2011, 118 (21) : 1059 - 1060
  • [45] Rapid CBFB-MYH11 diagnosis by one single MYH11 real-time PCR.
    Van der Reijden, BA
    Massop, M
    van de Locht, L
    De Witte, T
    Muus, P
    Jansen, JH
    BLOOD, 2002, 100 (11) : 327A - 328A
  • [46] Strikingly different molecular relapse kinetics in NPM1c, PML-RARA, RUNX1-RUNX1T1, and CBFB-MYH11 acute myeloid leukemias
    Ommen, Hans Beier
    Schnittger, Susanne
    Jovanovic, Jelena V.
    Ommen, Ingrid Beier
    Hasle, Henrik
    Ostergaard, Mette
    Grimwade, David
    Hokland, Peter
    BLOOD, 2010, 115 (02) : 198 - 205
  • [47] KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice
    Zhao, Ling
    Melenhorst, Jan J.
    Alemu, Lemlem
    Kirby, Martha
    Anderson, Stacie
    Kench, Maggie
    Hoogstraten-Miller, Shelley
    Brinster, Lauren
    Kamikubo, Yasuhiko
    Gilliland, D. Gary
    Liu, P. Paul
    BLOOD, 2012, 119 (06) : 1511 - 1521
  • [48] Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11
    Castilla, LH
    Wijmenga, C
    Wang, Q
    Stacy, T
    Speck, NA
    Eckhaus, M
    MarinPadilla, M
    Collins, FS
    WynshawBoris, A
    Liu, PP
    CELL, 1996, 87 (04) : 687 - 696
  • [49] Oncogenes PLAG1 and PLAGL2 synergize with CBFB-MYH11 in AML.
    Landrette, S
    Perrat, P
    Hensen, K
    de Ven, V
    Castilla, L
    BLOOD, 2002, 100 (11) : 85A - 85A
  • [50] Upregulation of CBFB induces resistance to RUNX1 inhibition in acute myeloid leukemia cells
    Noura, Mina
    Morita, Ken
    Tokushige, Chieko
    Maeda, Shintaro
    Sugiyama, Hiroshi
    Yoshida, Kenichi
    Ogawa, Seishi
    Kamikubo, Yasuhiko
    Adachi, Souichi
    CANCER SCIENCE, 2018, 109 : 855 - 855
12345