Title: Runx1 Is Indispensable for Leukemia Development Induced By Cbfb-MYH11

被引:0
|
作者
Zhen, Tao [1 ,2 ]
Kwon, Erika Mijin [2 ]
Hyde, R. Katherine [3 ,4 ]
Zhao, Ling [5 ]
Lopez, Guadalupe [1 ]
Alemu, Lemlem [6 ]
Liu, Paul P. [2 ]
机构
[1] NHGRI, Translat & Funct Genom Branch, NIH, Bethesda, MD 20892 USA
[2] NHGRI, Oncogenesis & Dev Sect, NIH, Bethesda, MD 20892 USA
[3] Univ Nebraska Med Ctr, Dept Biochem & Mol Biol, Omaha, NE USA
[4] Univ Nebraska Med Ctr, Fred & Pamela Buffet Canc Ctr, Omaha, NE USA
[5] NHGRI, Oncogenesis & Dev Sect, Bethesda, MD 20892 USA
[6] NHLBI, Hematol Branch, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1182/blood-2018-99-116930
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1337
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Runx1 Is Strictly Required for Cbfb-MYH11 Induced Leukemia Development
    Zhen, Tao
    Kwon, Erika Mijin
    Hyde, R. Katherine
    Zhao, Ling
    Lopez, Guadalupe
    Alemu, Lemlem
    Liu, Pu Paul
    BLOOD, 2016, 128 (22)
  • [2] Runx1 Is Required for Cbfb-MYH11 Activity During Primitive Hematopoiesis
    Hyde, R. Katherine
    Zhao, Ling
    Alemu, Lemlem
    Liu, Pu Paul
    BLOOD, 2011, 118 (21) : 596 - 596
  • [3] RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML
    Wang, Yiqian
    Hannon, Kira
    Richter, Lisa
    Becker, Michelle
    Garett, Lisa
    Rivas, Cecilia
    Alemu, Lemlem
    Zhao, Ling
    Liu, Pu Paul
    Hyde, R. Katherine
    BLOOD, 2016, 128 (22)
  • [4] Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice
    Hyde, R. K.
    Zhao, L.
    Alemu, L.
    Liu, P. P.
    LEUKEMIA, 2015, 29 (08) : 1771 - 1778
  • [5] Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice
    R K Hyde
    L Zhao
    L Alemu
    P P Liu
    Leukemia, 2015, 29 : 1771 - 1778
  • [6] Cbfb-MYH11 Can Block Hematopoiesis and Alter Gene Expression through Mechanisms Independent of Cbfb and Runx1 Repression
    Hyde, R. Katherine
    Kamikubo, Yasuhiko
    Alemu, Lemlem
    Zhao, Ling
    Wang, Chenwei
    Liu, Pu Paul
    BLOOD, 2008, 112 (11) : 277 - 277
  • [7] Role of Runx2 in Cbfb-MYH11 mediated acute myeloid leukemia.
    Kuo, YH
    Landrette, S
    Perrat, P
    Martinez, N
    Castilla, LH
    BLOOD, 2002, 100 (11) : 733A - 733A
  • [8] Cbfb/Runx1 repression-independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11
    Hyde, R. Katherine
    Kamikubo, Yasuhiko
    Anderson, Stacie
    Kirby, Martha
    Alemu, Lemlem
    Zhao, Ling
    Liu, P. Paul
    BLOOD, 2010, 115 (07) : 1433 - 1443
  • [9] Comprehensive Mutation Profile in Acute Myeloid Leukemia Patients with RUNX1-RUNX1T1 or CBFB-MYH11 Fusions
    Qin, Wei
    Chen, Xiayu
    Shen, Hong Jie
    Wang, Zheng
    Cai, Xiaohui
    Jiang, Naike
    Hua, Haiying
    TURKISH JOURNAL OF HEMATOLOGY, 2022, 39 (02) : 84 - 93
  • [10] The gene product of CBFB-MYH11
    Claxton, D
    Xie, QS
    Patel, S
    Deisseroth, AB
    Kornblau, S
    LEUKEMIA, 1996, 10 (09) : 1479 - 1485