Progress report on new antiepileptic drugs: A summary of the Third Eilat Conference

被引:37
作者
Bialer, M
Johannessen, SI
Kupferberg, HJ
Levy, RH
Loiseau, P
Perucca, E
机构
[1] NATL CTR EPILEPSY,SANDVIKA,NORWAY
[2] NINCDS,EPILEPSY BRANCH,NIH,BETHESDA,MD 20892
[3] UNIV WASHINGTON,DEPT PHARMACEUT,SEATTLE,WA 98195
[4] UNIV WASHINGTON,DEPT NEUROL SURG,SEATTLE,WA 98195
[5] UNIV BORDEAUX 1,HOSP PELLEGRIN,DEPT NEUROL,BORDEAUX,FRANCE
[6] UNIV PAVIA,DEPT INTERNAL MED & THERAPEUT,CLIN PHARMACOL UNIT,I-27100 PAVIA,ITALY
关键词
antiepileptic drug development; clinical trial design; drug approval;
D O I
10.1016/S0920-1211(96)00081-2
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The Third Eilat Conference on New Antiepileptic Drugs was held at the Royal Beach Hotel from May 27 to May 30, 1996. Epileptologists and scientists from 20 countries attended the conference, which was held to discuss critical issues in drug development, new antiepileptic drugs (AEDs) in development, progress reports and recent findings of newly marketed AEDs, the use of AEDs in special populations and their utilization in non-epileptic disorders. Over the last seven years, six new AEDs have been introduced worldwide and new information on their safety and efficacy has become available. These include felbamate, gabapentin, lamotrigine, oxcarbazepine, topiramate and vigabatrin. Drugs in development include those at an advanced stage, such as remacemide and tiagabine, as well as those just entering clinical trials, such as rufinamide (CGP 331010) and levetiracetam (ucb LO59). The following is a summary of the presentations for drugs in development and recent findings on newly marketed drugs.
引用
收藏
页码:299 / 319
页数:21
相关论文
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