Differentiating osteoradionecrosis from nasopharyngeal carcinoma tumour recurrence using 99Tcm-sestamibi SPECT/CT

被引：9

作者：

Tan, A. E. H. ^{[1
,2
]}

Ng, D. C. E.

机构：

[1] Singapore Gen Hosp, Dept Nucl Med, Singapore 169608, Singapore

[2] Singapore Gen Hosp, PET, Singapore 169608, Singapore

来源：

BRITISH JOURNAL OF RADIOLOGY | 2011年 / 84卷 / 1005期

关键词：

TECHNETIUM-99M-SESTAMIBI SPECT; THERAPY; OSTEONECROSIS; PATIENT; CANCER; TL-201;

D O I：

10.1259/bjr/60136051

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Osteoradionecrosis (ORN) of the base of skull is a known complication of external beam radiotherapy in the treatment of nasopharyngeal carcinoma, and is widely believed to be sequelae of radiation-induced endarteritis, leading to cellular death and fibrosis. Differentiating ORN from tumour recurrence is challenging and has direct clinical implications. We present a case where Tc-99(m)-sestamibi SPECT/CT was used to differentiate ORN from tumour recurrence and in which prior imaging using bone scintigraphy and fluorodeoxyglucose PET/CT were equivocal.

引用

页码：E172 / E175

页数：4

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