(2R)-8-Benzyl-2-[(S)-hydroxy(phenyl)methyl]-8-azabicyclo[3.2.1]octan-3-one

被引：6

作者：

Brzezinski, Krzysztof ^{[1
]}

Lazny, Ryszard ^{[2
]}

Sienkiewicz, Michal ^{[2
]}

Wojtulewski, Slawomir ^{[2
]}

Dauter, Zbigniew ^{[1
]}

机构：

[1] NCI, Synchrotron Radiat Res Sect, MCL, Argonne Natl Lab,Biosci Div, Argonne, IL 60439 USA

[2] Univ Bialystok, Inst Chem, PL-15399 Bialystok, Poland

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2012年 / 68卷

基金：

美国国家卫生研究院;

关键词：

ALDOL;

D O I：

10.1107/S1600536811053190

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The crystal of the title compound, C21H23NO2, was chosen from a conglomerate formed by a racemic mixture. An intramolecular hydrogen bond is formed between hydroxy group and heterocyclic N atom of the azabicyclo[ 3.2.1] octan-3-one system. The crystal structure is stabilized by C-H center dot center dot center dot O interactions between aliphatic C-H groups and the carbonyl O atom. For the title chiral crystal, the highly redundant and accurate diffraction data set collected with low energy copper radiation gave a Flack parameter of 0.12 (18) for anomalous scattering effects originating from O atoms.

引用

页码：o149 / o150

页数：11

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