Stem cells and pulmonary metamorphosis: New concepts in repair and regeneration

被引：32
作者：
Aliotta, JM
Passero, M
Meharg, J
Klinger, J
Dooner, MS
Pimentel, J
Quesenberry, PJ
机构：
[1] Roger Williams Med Ctr, Ctr Stem Cell Biol, Providence, RI 02908 USA
[2] Vet Adm Med Ctr, Providence, RI 02908 USA
来源：
JOURNAL OF CELLULAR PHYSIOLOGY | 2005年 / 204卷 / 03期
关键词：
D O I：
10.1002/jcp.20318
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Adult stem cells are likely to have much more versatile differentiation capabilities than once believed. Numerous studies have appeared over the past decade demonstrating the ability of adult stem cells to differentiate into a variety of cells from nonhematopoietic organs, includingthe lung.The goal of this review is to provide an overview of the growth factors which are thought to be involved in lung development and disease, describe the cells within the lung that are believed to replace cells that have been injured, review the studies that have demonstrated the transformation of bone marrow-derived stem cells into lung cells, and describe potential clinical applications with respect to human pulmonary disease.
引用
收藏
页码：725 / 741
页数：17
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