Simultaneous percutaneous atrial septal defect closure and percutaneous coronary intervention

Objective: To evaluate the possibility to perform both percutaneous coronary interventions (PCI) and atrial septal defect (ASD) transcatheter treatment during the same session. Transcatheter ASD closure is a well-established alternative to surgery and the treatment of choice for single vessel coronary artery disease (CAD) is accepted to be PCI. Methods: From January 2000 to December 2005, 985 patients were referred to our center for ASD closure. One hundred thirty four patients (59 males, mean age 58 +/- 4 years, range 45-72 years) were included in a prospective protocol of ASD transcatheter closure and coronary angiography. Results: In 7 patients we found a coronary artery disease. A combined single setting definitive percutaneous approach (ASD closure and PC]) was performed in 6 patients. The patient number 4 was judged unsuitable for PCI and then was referred for surgery. There was no acute intra-procedural complication in all patients; renal functions pre and post procedure showed no change despite the increase in the amount of contrast used. Conclusion: Our report showed the feasibility of both PCI and ASD transcatheter treatment during the same session.