Synthesis of Fluorinated and Non-Fluorinated Bicyclic Amidines through Ring-Closing Metathesis

被引：4
|
作者：
Cunat, Ana C. [1 ]
Flores, Sonia [2 ]
Oliver, Judit [1 ]
Fustero, Santos [2 ,3 ]
机构：
[1] Univ Valencia, Dept Quim Organ, Fac Quim, E-46100 Valencia, Spain
[2] Univ Valencia, Fac Farm, Dept Quim Organ, Valencia 46100, Spain
[3] Ctr Invest Principe Felipe, Lab Mol Organ, Valencia 46012, Spain
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 2011卷 / 36期
关键词：
Amidines; Nitrogen heterocycles; Metathesis; Fluorine; ASYMMETRIC-SYNTHESIS; EFFICIENT; PHARMACEUTICALS; ISOMERIZATION; HETEROCYCLES; ACTIVATION; CHEMISTRY; PATHWAY; PROFILE; ENTRY;
D O I：
10.1002/ejoc.201101091
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient method for the synthesis of fluorinated and non-fluorinated imidazoazepines by a ring-closing metathesis reaction as the key step is described. The influence of the fluorine atoms on the preparation of these bicyclic systems is also studied.
引用
收藏
页码：7317 / 7323
页数：7
相关论文
共 50 条
  • [31] Ring-closing metathesis for the synthesis of a molecular gyrotop
    Setaka, Wataru
    Higa, Sayaka
    Yamaguchi, Kentaro
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, 12 (21) : 3354 - 3357
  • [32] Synthesis of cyclitols via ring-closing metathesis
    Kornienko, A
    d'Alarcao, M
    TETRAHEDRON-ASYMMETRY, 1999, 10 (05) : 827 - 829
  • [33] Synthesis of "glycospirostanes" via ring-closing metathesis
    Czajkowska, Dorota
    Morzycki, Jacek W.
    Santillan, Rosa
    Siergiejczyk, Leszek
    STEROIDS, 2009, 74 (13-14) : 1073 - 1079
  • [34] Ring-closing metathesis in the synthesis of fused sultones
    Mondal, Shovan
    Debnath, Sudatshan
    TETRAHEDRON LETTERS, 2014, 55 (09) : 1577 - 1580
  • [35] Synthesis of cyclic enehydrazides by ring-closing metathesis
    Lebrun, Stephane
    Couture, Axel
    Deniau, Eric
    Grandclaudon, Pierre
    SYNTHESIS-STUTTGART, 2006, (20): : 3490 - 3494
  • [36] Synthesis of cyclic dipeptides by ring-closing metathesis
    Reichwein, JF
    Liskamp, RMJ
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2000, 2000 (12) : 2335 - 2344
  • [37] Morphological transitions in fluorinated and non-fluorinated parylenes
    Morgen, Michael
    Zhao, Jie-Hua
    Rhee, Seung-Hyun
    Ryan, E. Todd
    Ho, Huei-Min
    Plano, Mary Anne
    Ho, Paul S.
    Materials Research Society Symposium - Proceedings, 1999, 565 : 297 - 302
  • [38] Synthesis of Berkeleylactone A by Ring-Closing Alkyne Metathesis
    Schmidt, Frank
    Ammanath, Aparna Viswanathan
    Goetz, Friedrich
    Maier, Martin E.
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2023, 26 (36)
  • [39] Synthesis of vinyl fluorides by ring-closing metathesis
    Marhold, M
    Buer, A
    Hiemstra, H
    van Maarseveen, JH
    Haufe, G
    TETRAHEDRON LETTERS, 2004, 45 (01) : 57 - 60
  • [40] Synthesis of Macrocyclic β-Peptidomimetics by Ring-Closing Metathesis
    Dinh Hieu Tran
    Xuan Tu Nguyen
    Thi Minh Chau Tran
    Thuy Quynh Le
    Chang Ho Oh
    Dinh Hung Mac
    CHEMISTRYSELECT, 2020, 5 (39): : 12232 - 12235
12345