A modular assembly of chiral oxazolinylcarbene-rhodium complexes:: Efficient phosphane-free catalysts for the asymmetric hydrosilylation of dialkyl ketones

被引：207
作者：
Gade, LH [1 ]
César, V [1 ]
Bellemin-Laponnaz, S [1 ]
机构：
[1] Univ Strasbourg, Inst Le Bel, Lab Chim Organomet & Catalyse, UMR 7513, F-67070 Strasbourg, France
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 08期
关键词：
asymmetric catalysis; carbene ligands; hydrosilylation; ketones; rhodium;
D O I：
10.1002/anie.200353133
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel class of chiral bidentate ligands with a carbene and an oxazoline moiety is obtained by the coupling of N-arylimidazoles and a 2-bromooxazoline derivative. The rhodium complex 1 catalyzes the hydrosilylation of aryl alkyl ketones and otherwise problematic dialkyl ketones in high yields and good enantioselectivities (up to 95% ee).
引用
收藏
页码：1014 / 1017
页数：4
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