A modular assembly of chiral oxazolinylcarbene-rhodium complexes:: Efficient phosphane-free catalysts for the asymmetric hydrosilylation of dialkyl ketones

被引：207
作者：
Gade, LH [1 ]
César, V [1 ]
Bellemin-Laponnaz, S [1 ]
机构：
[1] Univ Strasbourg, Inst Le Bel, Lab Chim Organomet & Catalyse, UMR 7513, F-67070 Strasbourg, France
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 08期
关键词：
asymmetric catalysis; carbene ligands; hydrosilylation; ketones; rhodium;
D O I：
10.1002/anie.200353133
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel class of chiral bidentate ligands with a carbene and an oxazoline moiety is obtained by the coupling of N-arylimidazoles and a 2-bromooxazoline derivative. The rhodium complex 1 catalyzes the hydrosilylation of aryl alkyl ketones and otherwise problematic dialkyl ketones in high yields and good enantioselectivities (up to 95% ee).
引用
收藏
页码：1014 / 1017
页数：4
相关论文
共 49 条
[21]  
Gstcttmayr C. W. K., 2002, ANGEW CHEM, V114, P1421
[22]  
Gstöttmayr CWK, 2002, ANGEW CHEM INT EDIT, V41, P1363, DOI 10.1002/1521-3773(20020415)41:8<1363::AID-ANIE1363>3.0.CO
[23]  
2-G
[24]  
Helmchen G., 2000, ACCOUNTS CHEM RES, V33, P326
[25]  
Herrmann W. A., 2002, ANGEW CHEM, V114, P1342, DOI [DOI 10.1002/1521-3757(20020415)114:8<1342::AID-ANGE1342>3.0.CO
[26]  
2-A, DOI 10.1016/j.ccr.2014.12.019]
[27]  
Herrmann WA, 2002, ANGEW CHEM INT EDIT, V41, P1290, DOI 10.1002/1521-3773(20020415)41:8<1290::AID-ANIE1290>3.0.CO
[28]  
2-Y
[29]   N-heterocyclic carbenes [J].
Herrmann, WA ;
Kocher, C .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1997, 36 (20) :2162-2187
[30]   Chiral heterocyclic carbenes in asymmetric homogeneous catalysis [J].
Herrmann, WA ;
Goossen, LJ ;
Kocher, C ;
Artus, GRJ .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1996, 35 (23-24) :2805-2807
12345