Progress in reprogramming somatic cells into stem cells

被引：0
|
作者：
Qiu Xiao-Yan [2 ]
Li Yue-Min [1 ]
机构：
[1] SW Univ, Embryo Engn Lab, Chongqing 400715, Peoples R China
[2] SW Univ, Coll Anim Sci & Technol, Chongqing 400715, Peoples R China
来源：
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS | 2008年 / 35卷 / 04期
关键词：
differentiated cells(somatic cells); reprogramming; pluripotent cells(stem cells);
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent scientific achievements in cell and developmental biology have provided unprecedented opportunities for advances in biomedical research. The demonstration that fully differentiated cells can reverse their gene expression profile to that of pluripotent cells, and the successful derivation and culture of human embryonic stem cells (ESCs) have fuelled hopes for applications in regenerative medicine. Ethical issues concerning the use of cloned human embryos for the derivation of stem cells have stimulated the search for alternative methods for reversing differentiated cells into pluripotent cells. The present state of these reprogramming technologies will be reviewed and their relative success will be discussed.
引用
收藏
页码：368 / 372
页数：5
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