Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito

被引：15

作者：

Bezerra-Silva, Patricia C. ^{[1
]}

Santos, Jefferson C. ^{[1
]}

Santos, Geanne K. N. ^{[1
]}

Dutra, Kamilla A. ^{[1
]}

Santana, Andrea L. B. D. ^{[1
,2
]}

Maranhao, Claudia A. ^{[1
,3
]}

Nascimento, Marcia S. ^{[2
]}

Navarro, Daniela M. A. F. ^{[1
]}

Bieber, Lothar W. ^{[1
]}

机构：

[1] Univ Fed Pernambuco, Dept Quim Fundamental, Recife, PE, Brazil

[2] Univ Fed Pernambuco, Dept Antibiot, Recife, PE, Brazil

[3] Inst Fed Educ Ciencia & Tecnol Pernambuco, Recife, PE, Brazil

来源：

EXPERIMENTAL PARASITOLOGY | 2015年 / 153卷

关键词：

Hardwood; Maackiain; Medicarpin; Bowdichia virgilioides; Aedes aegypti; L; DIPTERA; CHEMICAL-COMPOSITION; MEDICINAL-PLANTS; ESSENTIAL OILS; DENGUE VECTOR; FLAVONOIDS; BRAZIL; CONSTITUENTS; OVIPOSITION; ISOFLAVONOIDS;

D O I：

10.1016/j.exppara.2015.03.018

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The larvicidal activities of extracts of three hardwood species (Hymenaea stigonorcapa, Anadenanthera colubrina and Bowdichia virgilioides) against 4th instar larvae of Aedes aegypti were evaluated using WHO guidelines. Extracts of H. stignocarpa and A. colubrina showed weak activity. The highest larvicidal effect was obtained with the cyclohexane extract of the heartwood of B. virgilioides, which caused 100% mortality at concentrations at 50 and 100 mu g/mL. Fraction toluene/EtOAc (8:2) from this extract showed larvicidal activity (LC50 = 34.90 +/- 1.27 mu g/mL). A mixture of two compounds identified as medicarpin and maackiain exhibited a very good larvicidal activity (sub-fraction 2, LC50 = 17.5 +/- 1.87 mu g/mL) and maackiain showed to be a strong larvicidal compound (LC50 = 21.95 +/- 1.34 mu g/mL). This result can be of value in the search for new natural larvicidal compounds from other hardwood plant extracts and presents the first report of B. virgilioides being used to control a mosquito vector. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：160 / 164

页数：5

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